General Information |
|
Product |
PACAP Peptide |
Description |
Antigenic Blocking Peptide Pituitary adenylate cyclase-activating polypeptide |
Verified Applications |
Immunodepletion, Immunocompetition |
Immunogen |
Synthetic peptide taken within amino acid region 125-176 on human Pituitary adenylate cyclase-activating polypeptide protein. |
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|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
|
|
Competition/Depletion assay |
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|
|
Uniprot # |
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Overview |
Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion. Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells. |
Molecular Function |
neuropeptide hormone activity peptide hormone receptor binding pituitary adenylate cyclase activating polypeptide activity pituitary adenylate cyclase-activating polypeptide receptor binding receptor binding signal transducer activity, downstream of receptor |
Subcellular Location |
Secreted |
Expression |
Interacts with ADCYAP1R1 (via N-terminal extracellular domain). |
Structure |
Belongs to the glucagon family. |
Alternative Nomenclature |
adenylate cyclase activating polypeptide 1 (pituitary) antibody PACAP antibody PACAP-related peptide antibody Pituitary adenylate cyclase-activating polypeptide 27 antibody Pituitary adenylate cyclase-activating polypeptide 38 antibody Pituitary adenylate cyclase-activating polypeptide antibody prepro-PACAP antibody PRP-48 antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
---|---|---|---|---|
|
PACA-101AP | |||
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PACA-BIOTIN | |||
|
PACA-FITC | |||
|
PC-PACA | |||
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