General Information
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Product
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Apelin Receptor Positive Control
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Verified Applications
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WB
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Immunogen
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Purified protein.
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Accession #
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NCBI: NP_005152
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Physical Properties
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Quantity
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5 Applications
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Volume
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Inquire
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Form
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Western Blot Positive Control
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Storage
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-20⁰C for long term storage
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Application Protocol
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Western Blot
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1:500
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Protein
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Uniprot #
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P35414
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Overview
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Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.
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Molecular Function
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Developmental protein, G-protein coupled receptor, Receptor, Transducer
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Subcellular Location
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Cell membrane, Multi-pass membrane protein
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Expression
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Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon.
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Structure
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Transmembrane, Transmembrane helix
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Alternative Nomenclature
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AGTRL1 ligand antibody
APEL antibody
Apelin-13 antibody
APJ endogenous ligand antibody
Apln antibody
XNPEP2 antibody
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