General Information |
|
Product |
DDIT3 Antibody FITC-Conjugated |
Description |
FITC-Conjugated DNA damage-inducible transcript 3 protein Antibody |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 60-160 on human GADD153 protein. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.57-0.68 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. |
Molecular Function |
Activator, Repressor, DNA binding |
Subcellular Location |
Cytoplasm, Nucleus |
Structure |
Heterodimer. Interacts with TCF7L2/TCF4, EP300/P300, HDAC1, HDAC5 and HDAC6. Interacts with TRIB3 which blocks its association with EP300/P300. Interacts with FOXO3, CEBPB and ATF4. |
Alternative Nomenclature |
C/EBP homologous protein antibody C/EBP zeta antibody CCAAT/enhancer binding protein homologous protein antibody CEBPZ antibody CHOP 10 antibody DDIT3 antibody DNA Damage Inducible Transcript 3 antibody GADD153 antibody Growth Arrest and DNA Damage Inducible Protein 153 antibody MGC4154 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
GADD153-101AP | |||
|
P-GADD153 | |||
|
GADD153-BIOTIN | |||
|
PC-GADD153 | |||
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