General Information |
|
Product |
IKAP Antibody FITC-Conjugated |
Description |
FITC-Conjugated IkappaB kinase complex-associated protein Antibody |
Verified Applications |
ELISA, IP, WB |
Host |
Chicken |
Species Cross Reactivity |
Mouse |
Immunogen |
Recombinant IkappaB kinase complex-associated protein. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.55-0.75 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgY |
Form |
FITC-Conjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:10,000 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
May act as a scaffold protein that may assemble active IKK-MAP3K14 complexes (IKKA, IKKB and MAP3K14/NIK). Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration. Involved in neurogenesis (PubMed:19185337). Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha-tubulin acetylation (PubMed:19185337). |
Molecular Function |
Phosphorylase kinase regulator activity |
Subcellular Location |
Cytoplasm, Nucleus |
Expression |
Widely expressed with highest levels in brain. |
Alternative Nomenclature |
DYS antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
IKAP-101Y | |||
|
IKAP-Y-BIOTIN | |||
|
P-IKAP | |||
|
PC-IKAP | |||
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