General Information |
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Product |
Ephrin Receptor A3 Antibody Western Blot Positive Control |
Description |
Western Blot Positive Control Ephrin Type-A Receptor 3 Antibody |
Verified Applications |
WB |
Immunogen |
Purified Protein |
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Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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Western Blot |
1:500 |
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Uniprot # |
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Overview |
Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. |
Molecular Function |
ATP binding; Nucleotide binding |
Subcellular Location |
Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted |
Expression |
Widely expressed. Highest level in placenta. |
Structure |
Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses. Forms a ternary EFNA5-EPHA3-ADAM10 complex mediating EFNA5 extracellular domain shedding. |
Alternative Nomenclature |
AW492086 antibody Cek4 antibody EC 2.7.10.1 antibody EK4 antibody End3 antibody Eph receptor A3 antibody EPH-like kinase 4 antibody EPH-like tyrosine kinase 1 antibody EphA3 antibody Ephrin type-A receptor 3 antibody ETK 1 antibody ETK antibody HEK 4 antibody HEK antibody Human embryo kinase 1 antibody Mek4 antibody MGC109882 antibody Receptor tyrosine kinase HEK antibody Tyro 4 antibody Tyrosine-protein kinase TYRO4 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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EPHAR3-301AP | |||
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EPHAR3-FITC | |||
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P-EPHAR3 | |||
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EPHAR3-BIOTIN | |||
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