General Information
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Product
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ELOVL4 Antibody BIOTIN-Conjugated
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Description
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BIOTIN-Conjugated Elongation of very long chain fatty acids protein 4 Antibody Mid-Region
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide corresponding to internal sequence amino acids 107-121 of Human ELOVL4.
Sequence:
SYICQSVDYSNNVHE
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Accession #
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NCBI: NP_073563
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.6 µg/µl in antibody stabilization buffer
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Form
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BIOTIN-Conjugated
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Clonality
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Polyclonal
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Determinant
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Mid-Region
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Storage
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-20⁰C for long term storage
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Application Protocol
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Immunohistochemistry |
1:100 |
Immunoprecipitation |
1:200 |
Western Blot
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1:500
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Protein
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Uniprot #
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Q9GZR5
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Overview
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Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Elongates C24:0 and C26:0 acyl-CoAs. Seems to represent a photoreceptor-specific component of the fatty acid elongation system residing on the endoplasmic reticulum. May be implicated in docosahexaenoic acid (DHA) biosynthesis, which requires dietary consumption of the essential alpha-linolenic acid and a subsequent series of three elongation steps. May play a critical role in early brain and skin development.
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Molecular Function
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Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism
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Subcellular Location
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Endoplasmic Reticulum; Membrane
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Expression
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Expressed in the retina and at much lower level in the brain. Ubiquitous, highest expression in thymus, followed by testis, small intestine, ovary, and prostate. Little or no expression in heart, lung, liver, or leukocates.
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Structure
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The di-lysine motif may confer endoplasmic reticulum localization.
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Alternative Nomenclature
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3-keto acyl-CoA synthase ELOVL4 antibody
ADMD antibody
Cancer/testis antigen 118 antibody
CT118 antibody
Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 4 antibody
ELOV L4 antibody
FLJ17667 antibody
FLJ92876 antibody
Stargardt disease 3 antibody
STGD2 antibody
STGD3 antibody
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