General Information
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Product
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PDE2A3 Antibody BIOTIN-Conjugated
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Description
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BIOTIN-Conjugated Phosphodiesterase 2A3 Antibody N-epitope
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide corresponding to region within amino acids 1-50 on N-terminus of human PDE2A3 protein.
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Specificity |
This antibody will detect PDE2A3 only. |
Accession #
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NCBI: NP_002590.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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BIOTIN-Conjugated
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Clonality
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Polyclonal
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Determinant
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N-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunohistochemistry |
1:100 |
Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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O00408
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Overview
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Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
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Molecular Function
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Calcium channel activity, cAMP binding, cGMP binding, cGMP-stimulated cyclic-nucleotide phosphodiesterase activity; drug binding; metal ion binding; protein homodimerization activity; TPR domain binding
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Subcellular Location
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Cell membrane; Lipid-anchor
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Expression
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Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas.
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Structure
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Belongs to the cyclic nucleotide phosphodiesterase family. PDE2 subfamily.
Contains 2 GAF domains.
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Alternative Nomenclature
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Phosphodiesterase 2A 3
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