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General Information
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Product
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RIPK5 Antibody Affinity Purified
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Description
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Affinity Purified Dual serine/threonine and tyrosine protein kinase Antibody
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Verified Applications
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ELISA, IMM, WB
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Host
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Rabbit
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Species Cross Reactivity
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Bovine, Human, Monkey, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 200-250 on human Dual serine/threonine and tyrosine protein kinase protein (RIPK5).
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Accession #
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GenBank: Q6XUX3.2
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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Q6XUX3
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Overview
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Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death.
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Molecular Function
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ATP binding; Protein serine/threonine kinase activity; Protein tyrosine kinase activity; ATP-binding; Nucleotide-binding
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Subcellular Location
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Cell junction, Cell membrane, Cytoplasm, Membrane
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Expression
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Predominantly expressed in skeletal muscle and testis. Expressed in basolateral and apical membranes of all tubular epithelia. Expressed in thin ascending limb of the loop of Henle and the distal convoluted tubule. Expressed in all layers of transitional ureteric epithelium and in the ureteric smooth-muscle cells. Weakly expressed in heart, brain, placenta, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine, white blood cells, stomach, spinal cord and adrenal gland. Is widely distributed in the CNS. Also detected in several tumor cell lines.
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Structure
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Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Contains 1 protein kinase domain.
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Alternative Nomenclature
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DSTYK antibody
Dual serine/threonine and tyrosine protein kinase antibody
Dusty PK antibody
Dusty protein kinase antibody
HDCMD38P antibody
KIAA0472 antibody
Receptor interacting protein kinase 5 antibody
Receptor interacting serine/threonine protein kinase 5 antibody
RIP homologous kinase antibody
RIPK5 antibody
SgK496 antibody
Sugen kinase 496 antibody
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RIPK5 Antibody FITC
RIPK5 Antibody BIOTIN
RIPK5 Blocking Peptide
RIPK5 Positive Control
