General Information |
|
Product |
THAP1 Antibody BIOTIN |
Description |
BIOTIN-Conjugated THAP domain-containing protein 1 Antibody |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human Predicted: Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 150-210 on human THAP domain-containing protein 1. |
Accession # |
GenBank: CAG33537 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5-1.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
BIOTIN-Conjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:10,000 |
Immunocytochemistry |
1:50-1:150 |
Immunohistochemistry |
1:50-1:150 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis. |
Molecular Function |
Identical protein binding, Sequence-specific DNA binding, Zinc ion binding |
Subcellular Location |
Nucleus > nucleoplasm, PML body |
Expression |
Highly expressed in heart, skeletal muscle, kidney and liver. Weaker expression in brain and placenta. |
Structure |
Belongs to the THAP1 family. |
Alternative Nomenclature |
Nuclear proapoptotic factor antibody THAP 1 antibody THAP domain containing apoptosis associated protein 1 antibody THAP domain containing protein 1 antibody THAP domain protein 1 antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
---|---|---|---|---|
|
THAP1-101AP | |||
|
THAP1-FITC | |||
|
P-THAP1 | |||
|
PC-THAP1 | |||
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