General Information
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Product
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CCR2 Antibody BIOTIN-Conjugated
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Description
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BIOTIN-Conjugated C-C chemokine receptor type 2 Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human
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Immunogen
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Synthetic peptide taken within amino acid region 20-70 on human CCR2 protein.
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Accession #
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NCBI: NP_955783
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.61-0.71 µg/µl in antibody stabilization buffer
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Form
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BIOTIN-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Western Blot
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1:500
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Protein
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Uniprot #
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P41597
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Overview
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Receptor for CCL2, CCL7 and CCL13 chemokines. Transduces a signal by increasing intracellular calcium ion levels. Alternative coreceptor with CD4 for HIV-1 infection.
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Molecular Function
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Host-virus interaction; GPCR; Transducer
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Subcellular Location
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Cell membrane; Mulipass membrane protein.
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Expression
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Induced; Up-regulated by CREB3
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Structure
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Binds to HIV-1 Tat. Interacts with ARRB1
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Alternative Nomenclature
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CC CKR 2 antibody
CD192 antibody
CKR2A antibody
CKR2B antibody
CMKBR2 antibody
MCP1 RECEPTOR antibody
Monocyte chemoattractant protein 1 receptor antibody
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