General Information

Product

GIRK4 Antibody Affinity Purified

Description

Affinity Purified G protein-activated inward rectifier potassium channel 4 Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 350-450 on human GIRK4 protein.

Accession #

NCBI: NP_000881

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.53-0.57 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:250

Protein

Uniprot #

P48544

Molecular Function

Potassium

Subcellular Location

Membrane; Multi-pass membrane protein

Structure

Belongs to inward rectifier-type potassium channel family

Alternative Nomenclature

Cardiac ATP sensitive potassium channel antibody

Cardiac inward rectifier antibody

CIR antibody

G protein activated inward rectifier potassium channel 4 antibody

GIRK-4 antibody

Heart KATP channel antibody

Inward rectifier K+ channel KIR3.4 antibody

IRK-4 antibody

KATP-1 antibody

KCNJ 5 antibody

KIR3.4 antibody

Potassium channel antibody

General Information

Product

Glucose transporter GLUT4 Antibody

Description

Affinity Purified Solute carrier family 2 , facilitated glucose transporter member 4 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 450-509 on mouse Solute carrier family 2, facilitated glucose transporter member 4 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DOT Blot

1:4,000

ELISA

1:4,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:1,000

Protein

Uniprot #

P14142

Overview

Insulin-regulated facilitative glucose transporter

Molecular Function

glucose transmembrane transporter activity;insulin-responsive hydrogen:glucose symporter activity

Subcellular Location

Cell membrane, Cytoplasm, Membrane

Expression

Skeletal and cardiac muscles; brown and white fat.

Structure

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily

Alternative Nomenclature

insulin-responsive antibody

Glucose transporter GLUT 4 antibody

GLUT 4 antibody

kug antibody

SLC 2A4 antibody

Solute carrier family 2, facilitated glucose transporter member 4 antibody

General Information

Product

Glucose Transporter GLUT1 Antibody

Verified Applications

ELISA, ICC/IF, IHC-FoFr, IHC-Fr, IHC-P, IP, WB, Immunomicroscopy

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide conjugated to KLH, corresponding to amino acids 478-492 of Human Glucose Transporter GLUT1. Peptide was covalently modified.

Sequence:

PEELFHPLGADSQV

Accession #

GenBank: AAC28635.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:12,000

Immunocytochemistry

1:50-1:200

Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Immunoprecipitation

1:200

Western Blot

1:5,000

Protein

Uniprot #

P11166

Overview

Facilitative glucose transporter.  May be responsible for constitutive or basal glucose uptake.

Molecular Function

Sugar Transport

Subcellular Location

Cell membrane; Multi-pass membrane protein; melanosome

Expression

Detected in erythrocytes.  Variable expression in many human tissues

Structure

Transmembrane helix

Alternative Nomenclature

DYT17 antibody

DYT18 antibody

erythrocyte/brain antibody

Erythrocyte/brain HepG2 glucose transporter antibody

Erythrocyte/hepatoma glucose transporter antibody

facilitated glucose transporter member 1 antibody

Glucose transporter 1 antibody

GLUT1 antibody

GLUT1DS antibody

GLUTB antibody

GT1 antibody

GTG1 antibody

Gtg3 antibody

GTR1_HUMAN antibody

HepG2 glucose transporter antibody

PED antibody

RATGTG1 antibody

SLC2A1 antibody

Solute carrier family 2 (facilitated glucose transporter), member 1 antibody

General Information

Product

Glucose Transporter GLUT10 Antibody 

Description

Affinity Purified Solute carrier family 2 (facilitated glucose transporter), member 10 Antibody

Verified Applications

ELISA, ICC/IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within C-terminal region, amino acids 500-536 of rat Glucose Transporter GLUT10 protein. Peptide was covalently modified and coupled to a carrier protein.

Accession #

NCBI:  EDL96452.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.54 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:100

DB

1:4,500

ELISA

1:4,500

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

UPI000155277B

Overview

Facilitative glucose transporter

Molecular Function

Sugar transport, Transport

Subcellular Location

Endomembranesystem; Multi-pass membrane protein; perinuclear region

Expression

Widely expressed; highest levels in liver and pancreas.

Structure

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Alternative Nomenclature

AA450473 antibody

facilitated glucose transporter member 10 antibody

Glucose transporter type 10 antibody

glut 10 antibody

MGC126706 antibody

SLC2A10 antibody

Solute carrier family 2 antibody

General Information

Product

GLUT12 Antibody

Description

Affinity Purified Solute carrier family 2 facilitated glucose transporter member 12 Antibody

Verified Applications

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide from the C-terminus of Rat GLUT12. 

Accession #

GenBank: EDL87731.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Dot Blot

1:4500

ELISA

1:4500

Immunoprecipitation

1:200

Western Blot

1:500. Predicted molecular weight 67 kDa.

Protein

Uniprot #

D3ZNG4

Overview

Substrate-specific transmembrane transporter activity

Molecular Function

Sugar Transport

Subcellular Location

Integral component of membrane

Structure

Belongs to major facilitator superfamily Sugart Transporter family.

Alternative Nomenclature

Glucose transporter type 12 antibody

GLUT8 antibody

SLC2A12 antibody

Solute carrier family 2 (facilitated glucose transporter) member 12 antibody

General Information

Product

Glucose Transporter 8 Antibody Affinity Purified

Description

Affinity Purified Solute carrier family 2, facilitated glucose transporter member 8 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse , Rat

Immunogen

Synthetic peptide taken within amino acid region 400-500 on GLUT8 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.56-0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9NY64

Overview

Insulin-regulated facilitative glucose transporter.  Binds cytochalasin B in glucose-inhibitable manner.

Molecular Function

Sugar Transport

Subcellular Location

Cell membrane; Multi-pass membrane protein; Cytoplasmic vessicle membrane

Expression

Highly expressed in testis; lower amounts in other tissues.  Down regulated by estrogen.

Structure

Interacts with AP2B1

Alternative Nomenclature

Glucose transporter type 8 antibody

Glucose transporter type X1 antibody

GLUT8 antibody

GLUTX1 antibody

solute carrier family 2 (facilitated glucose transporter) member 8 antibody

General Information

Product

Glucose Transporter 9 Antibody Affinity Purified

Description

Affinity Purified Solute carrier family 2, facilitated glucose transporter member 9 Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 50-570 on Glut 9 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,500

ELISA

1:4,500

Immunoprecipitation

1:200

Western Blot

1:500-1:750

Protein

Uniprot #

Q9NRM0

Overview

Urate and fructose transport.  Also transports glucose at lower rate.

Molecular Function

Sugar Transport

Subcellular Location

Membrane; Multi-pass membrane

Expression

Basolateral membranes of proximal renal tubular cells, liver and placenta.  Also found in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articiular cartilage.

Structure

Transmembrane helix

Alternative Nomenclature

glucose transporter 9 antibody

GLUT9 antibody

GLUTX antibody

Human glucose transporter like protein 9 antibody

SLC2A9 antibody

Solute carrier family 2, facilitated glucose transporter member 9 antibody

UAQTL2 antibody

Urate voltage driven efflux transporter 1 antibody

URATv1 antibody

General Information

Product

GAPDH Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 75-150 on mouse Glyceraldehyde-3-phosphate dehydrogenase protein.

Accession #

NCBI:  NP_032110.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P16858

Overview

Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively.

Molecular Function

Oxidoreductase, Transferase

Subcellular Location

Cytoplasm, Cytoskeleton, Nucleus

Expression

brain; cerebullum; heart; kidney; liver; skeletal muscle

Structure

Homotetramer

Alternative Nomenclature

AI747587 antibody

cytoplasmic antibody

EC 1.1.1.8 antibody

FLJ26652 antibody

G3PD antibody

Gdc1 antibody

Gdp1 antibody

Glycerol 3 phosphate dehydrogenase 1 antibody

Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic antibody

GPDH antibody

GPDH-C antibody

HTGTI antibody

MGC93453 antibody

MGPD antibody

mKIAA4010 antibody

General Information

Product

Isocitrate dehydrogenase Antibody

Description

Affinity Purified IDH1 Antibody

Verified Applications

CM, ELISA, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 350-414 on human Isocitrate dehydrogenase.

Accession #

GenBank: CAG38738.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61-0.63 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:100

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q6FI37

Overview

Catalytic activity: Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.  Binds 1 magnesium or manganese ion per subunit as cofactor.

Molecular Function

Magnesium; Manganese; Metal-binding; NADP

Subcellular Location

Cytoplasm; Peroxisome

Structure

Belongs to icocitrate and isopropylmalate dehydorgenases family

Alternative Nomenclature

Cytosolic NADP isocitrate dehydrogenase antibody

Epididymis luminal protein 216 antibody

Epididymis secretory protein Li 26 antibody

HEL-216 antibody

ICDH antibody

IDCD antibody

IDH antibody

Idh1 antibody

IDP antibody

IDPC antibody

Isocitrate dehydrogenase [NADP] cytoplasmic antibody

NADP dependent isocitrate dehydrogenase cytosolic antibody

NADP(+)-specific ICDH antibody

Oxalosuccinate decarboxylase antibody

PICD antibody

General Information

Product

IP3 receptor Antibody Affinity Purified

Description

Affinity Purified Inositol 1,4,5-trisphosphate receptor type  isoform 1 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on human ITPR subtype 1 protein.

Accession #

NCBI:  NP_001093422.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.52-0.63 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q14643

Overview

Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).

Molecular Function

Calcium channel, Ion channel, Ligand-gated ion channel, Receptor

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein

Expression

Widely expressed

Structure

Homotetramer. Interacts with TRPC4. The PPXXF motif binds HOM1, HOM2 and HOM3. Interacts with RYR1, RYR2, ITPR1, SHANK1 and SHANK3. Interacts with ERP44 in a pH-, redox state- and calcium-dependent manner which results in the inhibition the calcium channe

Alternative Nomenclature

5-trisphosphate receptor antibody

DKFZp313N1434 antibody

inositol 1 4 5 triphosphate receptor type 1 antibody

Inositol 1 antibody

InsP3R1 antibody

IP3 antibody

IP3 receptor antibody

IP3R1 antibody

ITPR 1 antibody

SCA15 antibody

SCA16 antibody

SCA29 antibody

Type 1 inositol 1 4 5 trisphosphate receptor antibody

Type 1 inositol 1 antibody