General Information

Product

DRP1 Antibody

Description

Dynamin-related Protein 1 Antibody

Verified Applications

ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

D. Melanogaster, Human, Mouse, Rat

Immunogen

Synthetic peptide within 450-490 on human DRP1 protein.

Accession #

GenBank: BAC06576.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.68 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Clonality

Polyclonal

Storage

-20°C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:450

Protein

Uniprot #

Q8K1M6

Overview

Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism.

Molecular Function

GTP-binding, Lipid-binding, Nucleotide-binding

Subcellular Location

Golgi apparatus; Peripheral membrane protein; peroxisome; Mitochondrion outer membrane; Clathrin-coated pit; synaptic vesicle membrane

Expression

Expressed in the cerebellum and in several regions of the cerebrum and diencephalon

Structure

Homotetramer; dimerizes through the N-terminal GTP-middle region of one molecule binding to the GED domain of another DNM1L molecule. Oligomerizes in a GTP-dependent manner to form membrane-associated tubules with a spiral pattern. Can also oligomerize to form multimeric ring-like structures.

Alternative Nomenclature

DLP1 antibody

dnm1l antibody

Dnm1p/Vps1p-like protein antibody

dnml1 antibody

DRP1 antibody

DVLP antibody

Dymple antibody

Dynamin 1 like antibody

Dynamin family member proline-rich carboxyl-terminal domain less antibody

Dynamin like protein antibody

Dynamin-like protein 4 antibody

Dynamin-related protein 1 antibody

DYNIV 11 antibody

EMPF antibody

FLJ41912 antibody

HdynIV antibody

VPS1 antibody

General Information

Product

EHD1 Antibody

Description

Affinity Purified EH domain-containing protein 1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken wtihin amino acid region 515-565 on human EH-domain containing protein 1.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.58 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9H4M9

Overview

Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Plays a role in myoblast fusion. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth.

Molecular Function

Rab GTPase binding; ATP binding; calcium ion binding

Subcellular Location

Cell membrane, Endosome, Membrane

Expression

testis

Structure

Homooligomer, and heterooligomer with EHD2, EHD3 and EHD4, ATP-binding is required for heterooligomerization.

Alternative Nomenclature

CDABP0131 antibody

EH domain containing 1 antibody

FLJ42622 antibody

FLJ44618 antibody

H PAST antibody

PAST antibody

PAST1 antibody

Testilin antibody

General Information

Product

Prostaglandin E2 receptor EP3 subtype Antibody

Description

Affinity Purified Prostaglandin E2 Receptor subtype Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse

Immunogen

Synthetic peptide taken within amino acid region 300-350 on human Prostaglandin E2 receptor EP3 subtype.

Accession #

NCBI:  NP_942010.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-0.6 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Immunoprecipitation

1:250

Western Blot

1:500

Protein

Uniprot #

P43115

Overview

Receptor for prostaglandin E2 (PGE2); the EP3 receptor may be involved in inhibition of gastric acid secretion, modulation of neurotransmitter release in central and peripheral neurons, inhibition of sodium and water reabsorption in kidney tubulus and contraction in uterine smooth muscle. The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G-I proteins, and to an elevation of intracellular calcium. The various isoforms have identical ligand binding properties but can interact with different second messenger systems (By similarity).

Molecular Function

Prostaglandin E receptor activity, G-protein coupled receptor

Subcellular Location

Cell membrane; Multi-pass membrane

Expression

Expressed in small intestine, heart, pancreas, gastric fundic mucosa, mammary artery and pulmonary vessels.

Structure

Belongs to the G-protein coupled receptor 1 family.

Alternative Nomenclature

EP 2 antibody

Human prostaglandin E2 receptor antibody

PGE2 receptor EP2 subtype antibody

Prostaglandin E receptor 2 EP2 subtype antibody

PTGER2 antibody

General Information

Product

FeSODB1 Antibody Affinity Purified

Description

Affinity Purified Fe superoxide dismutase Antibody

Verified Applications

ELISA, WB

Host

Chicken

Species Cross Reactivity

Leishmania infantum

Immunogen

Purified peptide from FeSODB1 protein.

Accession #

GenBank: AAQ14560.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q71S88

Overview

Destroys radicals that are toxic to biological systems, and are normally produced within the cells

Molecular Function

Oxireductase, Metal ion bonding

Alternative Nomenclature

FESOD antibody

Iron superoxide dismutase, putative antibody

Superoxide dismutase antibody

General Information

Product

FSH Antibody

Description

Affinity Purified Follicle stimulating hormone Antibody

Verified Applications

CM, ELISA, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-60 on human FSH protein.

Accession #

GenBank: ABD84005

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.71 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

Dot Blot

1:50,000

ELISA

1:50,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Western Blot

1:500

Protein

Uniprot #

Q1W658

Overview

Binds to activin directly and serves as an activin antagonist.  Acts as a specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone.

Subcellular Location

Secreted

Structure

Monomer

Alternative Nomenclature

Follicle stimulating hormone receptor isoform 1 antibody

Follitropin receptor antibody

FSH receptor antibody

FSH-R antibody

FSHRO antibody

LGR1 antibody

MGC141667 antibody

MGC141668 antibody

ODG1 antibody

ovarian dysgenesis 1 antibody

General Information

Product

Glucose Transporter GLUT10 Antibody 

Description

Affinity Purified Solute carrier family 2 (facilitated glucose transporter), member 10 Antibody

Verified Applications

ELISA, ICC/IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within C-terminal region, amino acids 500-536 of rat Glucose Transporter GLUT10 protein. Peptide was covalently modified and coupled to a carrier protein.

Accession #

NCBI:  EDL96452.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.54 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:100

DB

1:4,500

ELISA

1:4,500

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

UPI000155277B

Overview

Facilitative glucose transporter

Molecular Function

Sugar transport, Transport

Subcellular Location

Endomembranesystem; Multi-pass membrane protein; perinuclear region

Expression

Widely expressed; highest levels in liver and pancreas.

Structure

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Alternative Nomenclature

AA450473 antibody

facilitated glucose transporter member 10 antibody

Glucose transporter type 10 antibody

glut 10 antibody

MGC126706 antibody

SLC2A10 antibody

Solute carrier family 2 antibody

General Information

Product

Isocitrate dehydrogenase Antibody

Description

Affinity Purified IDH1 Antibody

Verified Applications

CM, ELISA, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 350-414 on human Isocitrate dehydrogenase.

Accession #

GenBank: CAG38738.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61-0.63 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:100

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q6FI37

Overview

Catalytic activity: Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.  Binds 1 magnesium or manganese ion per subunit as cofactor.

Molecular Function

Magnesium; Manganese; Metal-binding; NADP

Subcellular Location

Cytoplasm; Peroxisome

Structure

Belongs to icocitrate and isopropylmalate dehydorgenases family

Alternative Nomenclature

Cytosolic NADP isocitrate dehydrogenase antibody

Epididymis luminal protein 216 antibody

Epididymis secretory protein Li 26 antibody

HEL-216 antibody

ICDH antibody

IDCD antibody

IDH antibody

Idh1 antibody

IDP antibody

IDPC antibody

Isocitrate dehydrogenase [NADP] cytoplasmic antibody

NADP dependent isocitrate dehydrogenase cytosolic antibody

NADP(+)-specific ICDH antibody

Oxalosuccinate decarboxylase antibody

PICD antibody

General Information

Product

IP3 receptor Antibody Affinity Purified

Description

Affinity Purified Inositol 1,4,5-trisphosphate receptor type  isoform 1 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on human ITPR subtype 1 protein.

Accession #

NCBI:  NP_001093422.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.52-0.63 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q14643

Overview

Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).

Molecular Function

Calcium channel, Ion channel, Ligand-gated ion channel, Receptor

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein

Expression

Widely expressed

Structure

Homotetramer. Interacts with TRPC4. The PPXXF motif binds HOM1, HOM2 and HOM3. Interacts with RYR1, RYR2, ITPR1, SHANK1 and SHANK3. Interacts with ERP44 in a pH-, redox state- and calcium-dependent manner which results in the inhibition the calcium channe

Alternative Nomenclature

5-trisphosphate receptor antibody

DKFZp313N1434 antibody

inositol 1 4 5 triphosphate receptor type 1 antibody

Inositol 1 antibody

InsP3R1 antibody

IP3 antibody

IP3 receptor antibody

IP3R1 antibody

ITPR 1 antibody

SCA15 antibody

SCA16 antibody

SCA29 antibody

Type 1 inositol 1 4 5 trisphosphate receptor antibody

Type 1 inositol 1 antibody

General Information

Product

LAMP1 Antibody

Description

Affinity Purified Lysosome-associated membrane glycoprotein 1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 300-350 on human LAMP1 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P11279

Overview

Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.

Molecular Function

Enzyme binding

Subcellular Location

Cell membrane, single-pass type I membrane protein, endosome membrane, lysosome membrane (Note:This protein shuttles between lysosomes, endosomes, and plasma membrane. Colocalizes with OSBPL1A at the late endosome)

Alternative Nomenclature

CD107 antigen like family member A antibody

LAMP 1 antibody

LAMPA antibody

LGP120 antibody

lgpA antibody

Lysosomal Associated Membrane Protein 1 antibody

General Information

Product

LOXL1 Antibody

Description

Affinity Purified Loxl1 protein Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 570-607 on rat LOXL1 protein.

Accession #

GenBank: AAH03973.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.66 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:20,000-1:50,000

Western Blot

1:500-1:1,000

Protein

Uniprot #

P97873

Overview

Active on elastin and collagen substrates.

Molecular Function

Copper ion binding, oxidereductase activity acting on the CH-NH2 group of donors and oxygen as accecptor

Subcellular Location

secreted, extracellular space

Alternative Nomenclature

Lysyl oxidase like 1 antibody

LOL antibody

Lysyl oxidase homolog 1 antibody

Lysyl oxidase like protein 1 antibody