Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction.
Molecular Function
Lyase
Subcellular Location
Membrane; Single-pass type I membrane protein
Expression
Expressed only in the eye.
Structure
Belongs to the adenylyl cyclase-class-4/guanylyl cyclase family. Contains 1 guanylate cyclase domain. Contains 1 protein kinase domain.
Fabgennix PGCFAntibody has been used in 1 Publication
Liu, Cambrian Y., Scott E. Fraser, and David S. Koos. "Grueneberg ganglion olfactory subsystem employs a cGMP signaling pathway." Journal of Comparative Neurology 516.1 (2009): 36-48.PMID19565523
Immunofluorescence, Western Blot; Mouse
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