PDE4D1 Antibody FITC

General Information

Product

PDE4D1 Antibody FITC-Conjugated

Description

FITC-Conjugated Phosphodiesterase 4D1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Chicken, Mouse, Rat

Immunogen

Synthetic peptide from unique region near N-terminus of PDE4D1 variant.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.73 µg/µl in antibody stabilization buffer

Form

FITC-Conjugated

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Overview

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Molecular Function

Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding

Subcellular Location

Apical cell membrane, Cytoplasm, Membrane

Expression

Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.

Structure

Homodimer for the long isoforms. Isoforms with truncated N-termini are monomeric. Isoform 3 is part of a ternary complex containing PRKAR2A, PRKAR2B and AKAP9. Interacts with PDE4DIP. Identified in a complex composed of RYR1, PDE4D, PKA, FKBP1A and protein phosphatase 1 (PP1).

Alternative Nomenclature

cAMP specific 3',5' cyclic phosphodiesterase 4D antibody

DKFZp686M11213 antibody

5''-cyclic phosphodiesterase 4D antibody

cAMP specific phosphodiesterase 4D antibody

cAMP specific phosphodiesterase PDE4D antibody

DPDE 3 antibody

Dunce like phosphodiesterase E3 antibody

FLJ97311 antibody

HSPDE4D antibody

PDE 43 antibody

PDE4DN2 antibody

Phosphodiesterase E3 dunce homolog Drosophila antibody

STRK1 antibody