General Information
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Product
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MAPK3 Antibody FITC-Conjugated
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Description
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FITC-Conjugated Mitogen-activated protein kinase 3 Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Chicken
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 300-350 on human Mitogen-activated protein kinase 3.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgY
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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P27361
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Overview
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Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors.
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Molecular Function
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Kinase, Serine/threonine-protein kinase, Transferase
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Subcellular Location
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Cytoplasm, Nucleus
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Structure
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The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
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Alternative Nomenclature
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Mitogen-activated protein kinase 3 Antibody MAP kinase 3 Antibody
MAPK 3 Antibody
ERT2 Antibody
Extracellular signal-regulated kinase 1 Antibody ERK-1 Antibody
Insulin-stimulated MAP2 kinase Antibody
MAP kinase isoform p44 Antibody p44-MAPK Antibody Microtubule-associated protein 2 kinase Antibody
p44-ERK1 Antibody
MAPK3 Antibody
ERK1 Antibody
PRKM3 Antibody
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