General Information |
|
Product |
BST2 Antibody FITC-Conjugated |
Description |
FITC-Conjugated Bonemarrow stromal antigen 2 Antibody N-epitope |
Verified Applications |
ELISA, CM, ICC, IF, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human |
Immunogen |
N-epitope Synthetic peptide taken within amino acid region 1-50 on human Bonemarrow stromal antigen 2 protein. |
Accession # |
GenBank: BAD96844 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.62 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Determinant |
N-epitope |
Storage |
-20⁰C for long term storage |
|
|
Confocal Microscopy |
1:200 |
DB |
1:2,000 |
ELISA |
1:2,000 |
Immunocytochemistry |
1:200 |
Immunofluorescence |
1:200 |
Immunohistochemistry |
1:200 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500-1:1,000 |
|
|
Uniprot # |
|
Overview |
IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells. |
Molecular Function |
Antiviral defense; B-cell activation; Immunity; Innate immunity |
Subcellular Location |
Gogli apparatus, trans-golgi network; Cell membrane, Single-pass type II membrane protein. Lipid anchor, GPI anchor; Late endosome; Membrane raft; Cytoplasm; Apical cell membrane |
Expression |
Liver, lung, heart and placenta. Lower levels in pancreas, kidney, skeletal msucle and brain. Overexpressed in multiple myeloma cells. B-cells, T-cells, monocytes, NK cells and dendritic cells. Induced by type I interforns. Down regulated by viral antagonistic factors. |
Structure |
Parallel homodimer; disulfide linked. Cytoplasmic domain interacts with ARHGAP44 and MMP14. |
Alternative Nomenclature |
Bone marrow stromal antigen 2 antibody Bone marrow stromal cell antigen 2 antibody BST 2 antibody CD 317 antibody CD317 antigen antibody HM1.24 antigen antibody NPC A 7 antibody Tetherin antibody |
Protein information supplied by UniProt
Fabgennix BST2 Antibody has been used in 3 Publications |
|
Sayeed, Aejaz et al. “Aberrant Regulation of the BST2 (Tetherin) Promoter Enhances Cell Proliferation and Apoptosis Evasion in High Grade Breast Cancer Cells.” Ed. Aamir Ahmad. PLoS ONE 8.6 (2013): e67191. PMC3688682
|
Immunocytochemistry, Immunohistochemistry, Western Blot; Human |
Cao, Wei et al. “Regulation of TLR7/9 Responses in Plasmacytoid Dendritic Cells by BST2 and ILT7 Receptor Interaction.” The Journal of Experimental Medicine 206.7 (2009): 1603–1614. PMC2715090
|
Western Blot; Human |
Cai, Dongqing et al. “Up-Regulation of Bone Marrow Stromal Protein 2 (BST2) in Breast Cancer with Bone Metastasis.” BMC Cancer 9 (2009): 102. PMC2674058
|
Immunohistochemistry, Western Blot; Human |
Publishing research using BST2-201AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
|
BST2-201AP | |||
|
P-BST2.10 | |||
|
BST2.10-BIOTIN | |||
|
PC-BST2 | |||
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