General Information

Product

GPCR GPR120 Antibody

Description

Affinity Purified Free fatty acid receptor A4 Antibody N-epitope

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

N-epitope synthetic peptide taken within amino acid region 1-80 on human FFAR4 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.58-0.59 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q5NUL3

Overview

Functions as a receptor for medium and long chain free fatty acids,signals through a G(q)/G(11)-coupled pathway.  Functions as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects.

Molecular Function

G-protein coupled receptor, Transducer, Receptor, Fatty acid binding

Subcellular Location

Cell membrane; Multipass membrane protein

Expression

Expression in intestinal tract with high expression in adipose tissue, small intestine and pancreas

Structure

Interacts with ARRB2 subsequent to docosahexaenoic acid stimulation

Alternative Nomenclature

G protein coupled receptor 120 antibody

G protein coupled receptor 129 antibody

G protein coupled receptor GT01 antibody

G protein coupled receptor PGR4 antibody

GPR 120 antibody

GPR 129 antibody

GT01 antibody

HGNC:19345 antibody

MGC119984 antibody

O3FAR1 antibody

Omega-3 fatty acid receptor 1 antibody

PGR 4 antibody

General Information

Product

MC3 Receptor Antibody

Description

Affinity Purified Melanocortin 3 receptor Antibody Mid-Region

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequences on MC3r protein.

Accession #

GenBank: AAD41351.1 

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid-Region

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q01726

Overview

Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane, Membrane

Expression

Cerebellum;testis;Melanocytes and corticoadrenal tissue.

Alternative Nomenclature

BMIQ9 antibody

MC3 antibody

Melanocortin 3 receptor antibody

OB20 antibody

Obesity quantitative trait locus antibody

OQTL antibody

General Information

Product

MC3 Receptor Antibody

Description

Affinity Purified Melanocortin 3 receptor Antibody C-epitope

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequences on MC3r protein.

Accession #

GenBank: AAO72726.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P41968

Overview

Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase.

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane, Membrane

Expression

Brain, placental, and gut tissues.

Structure

Belongs to the G-protein coupled receptor 1 family.

Alternative Nomenclature

BMIQ9 antibody

MC3 antibody

Melanocortin 3 receptor antibody

OB20 antibody

Obesity quantitative trait locus antibody

OQTL antibody

General Information

Product

MC3 Receptor Antibody

Description

Affinity Purified Melanocortin 3 receptor Antibody N-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequences on MC3r protein.

Accession #

GenBank: AAD41351.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q01726

Overview

Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane, Membrane

Expression

Cerebellum; testis; Melanocytes and corticoadrenal tissue.

Alternative Nomenclature

BMIQ9 antibody

MC3 antibody

MC3 R antibody

Melanocortin 3 receptor antibody

OB20 antibody

Obesity quantitative trait locus antibody

OQTL antibody

General Information

Product

Prolactin Antibody Affinity Purified

Description

Affinity Purified Prolactin Antibody C-epitope

Verified Applications

CM, ELISA, ICC, IHC, IF, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

C-epitope specific synthetic peptide taken within amino acid region 100-200 on human Prolactin protein.

Accession #

GenBank:  CAA38264.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:100

Dot Blot

1:50,000

ELISA

1:50,000

Immunocytochemistry

1:100

Immunohistochemistry

1:100

Western Blot

1:500

Protein

Uniprot #

P01236

Overview

Prolactin acts primarily on the mammary gland by promoting lactation.

Molecular Function

prolactin receptor binding, hormone

Subcellular Location

Secreted

Alternative Nomenclature

Decidual prolactin antibody

Lactogenic Hormone antibody

Luteotropic Hormone antibody

Mammotropin antibody

PRL antibody

General Information

Product

Prolactin Antibody

Description

Affinity Purified Prolactin Antibody N-epitope

Verified Applications

CM, ELISA, ICC, IHC, IF, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-100 on human Prolactin protein.

Accession #

GenBank:  CAA38264.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.7 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:100

Dot Blot

1:50,000

ELISA

1:50,000

Immunocytochemistry

1:100

Immunohistochemistry

1:100

Western Blot

1:500

Protein

Uniprot #

P01236

Overview

Prolactin acts primarily on the mammary gland by promoting lactation.

Molecular Function

prolactin receptor binding, hormone

Subcellular Location

Secreted

Alternative Nomenclature

Decidual prolactin antibody

Lactogenic Hormone antibody

Luteotropic Hormone antibody

Mammotropin antibody

PRL antibody

General Information

Product

Syndecan-1 Antibody Affinity Purified

Description

Affinity Purified Syndecan 1 Antibody C-epitope

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

C-epitope synthetic peptide taken within amino acid region 250-350 on human Syndecan-1 protein.

Accession #

GenBank: AAH08765.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.61 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P18827

Overview

Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.

Molecular Function

Protein C-terminus binding

Subcellular Location

Membrane; Single-pass type I membrane protein

Structure

Interacts with CDCP1. Interacts (via C-terminus) with TIAM1 (via PDZ domain).

Alternative Nomenclature

CD 138 antibody

Heparan sulfate proteoglycan fibroblast growth factor receptor antibody

SDC 1 antibody

SDC antibody

syndecan proteoglycan 1 antibody

General Information

Product

Syndecan-1 Antibody Affinity Purified

Description

Affinity Purified Syndecan 1 Antibody N-epitope

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

N-epitope synthetic peptide taken within amino acid region 1-100 on human Syndecan-1 protein.

Accession #

GenBank: AAH08765.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.61 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P18827

Overview

Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.

Molecular Function

Protein C-terminus binding

Subcellular Location

Membrane; Single-pass type I membrane protein

Structure

Interacts with CDCP1. Interacts (via C-terminus) with TIAM1 (via PDZ domain).

Alternative Nomenclature

CD 138 antibody

Heparan sulfate proteoglycan fibroblast growth factor receptor antibody

SDC 1 antibody

SDC antibody

syndecan proteoglycan 1 antibody

General Information

Product

ELOVL1 Antibody

Description

Affinity Purified Elongation of very long chain fatty acids protein 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Predicted: Mouse

Immunogen

Synthetic peptide taken within amino acid region 148-198 on human Elongation of very long chain fatty acids protein 1.

Accession #

NCBI:  NP_001243331

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9BW60

Overview

Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.

Molecular Function

Transferase; Fatty acid biosynthesis & metabolism; Lipid biosynthesis & metabolism

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein

Expression

Ubiquitous

Structure

The di-lysine motif may confer endoplasmic reticulum localization.

Alternative Nomenclature

3 keto acyl CoA synthase ELOVL1 antibody

CGI 88 antibody

Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 1 antibody

Elongation of very long chain fatty acids protein 1 antibody

ELOVL 1 antibody

ELOVL FA elongase 1 antibody

ELOVL fatty acid elongase 1 antibody

ELOVL1 antibody

Ssc1 antibody

Very-long-chain 3-oxoacyl-CoA synthase 1 antibody

General Information

Product

SERINC4 Antibody

Description

Affinity Purified Serine incorporator 4 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 350-400 on human Serine incorporator 4 protein.

Accession #

NCBI: NP_001244960

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

A6NH21

Overview

Incorporates a polar amino acid serine into membranes and facilitates the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids.

Molecular Function

L-serine transmembrane transporter activity

Subcellular Location

Membrane; Multi-ass membrane protein

Structure

Belongs to the TDE1 family

Alternative Nomenclature

FLJ40363 antibody

SERC4_HUMAN antibody

SERINC4 antibody

Serine incorporator 4 antibody