General Information

Product

CCR1 Antibody

Description

Affinity Purified Chemokine (C-C motif) receptor 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on mouse CCR1 protein.

Accession #

GenBank: AAH64991

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P32246

Overview

C-C type chemokine receptor that binds MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3.  Also binds less efficiently to MIP-1-beta or MCP-1.  Subsequently transduces a signal by increasing the intracellular calcium ion level.  Also responsible for affecting stem cell proliferation.

Molecular Function

GPCR; Receptor; Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Hematopoietic cells

Structure

Belongs to G-protein coupled receptor 1 family.  Interacts with CREB3.

Alternative Nomenclature

C C chemokine receptor type 1 antibody

C C CKR 1 antibody

CCR-1 antibody

CD191 antibody

Chemokine C C motif receptor 1 antibody

CKR 1 antibody

CMKBR1 antibody

CMKR 1 antibody

HM145 antibody

LD78 receptor antibody

Macrophage inflammatory protein 1 alpha receptor antibody

RANTES R antibody

SCYAR1 antibody

General Information

Product

CCR1 Antibody Affinity Purified

Description

Affinity Purified Chemokine (C-C motif) receptor 1 Antibody

Verified Applications

ELISA, WB

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human CCR1 protein.

Accession #

GenBank: AAH64991

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P32246

Overview

C-C type chemokine receptor that binds MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3.  Also binds less efficiently to MIP-1-beta or MCP-1.  Subsequently transduces a signal by increasing the intracellular calcium ion level.  Also responsible for affecting stem cell proliferation.

Molecular Function

GPCR; Receptor; Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Hematopoietic cells

Structure

Belongs to G-protein coupled receptor 1 family.  Interacts with CREB3.

Alternative Nomenclature

C C chemokine receptor type 1 antibody

C C CKR 1 antibody

CCR-1 antibody

CD191 antibody

Chemokine C C motif receptor 1 antibody

CKR 1 antibody

CMKBR1 antibody

CMKR 1 antibody

HM145 antibody

LD78 receptor antibody

Macrophage inflammatory protein 1 alpha receptor antibody

RANTES R antibody

SCYAR1 antibody

General Information

Product

CCR6 Antibody

Description

Affinity Purified C-C chemokine receptor type 6 Antibody

Verified Applications

ELISA, IHC, IP, WB

Species Cross Reactivity

Human, Mouse

Immunogen

Synthetic peptide taken within amino acid region 1-100 on human C-C chemokine receptor type 6 protein.

Accession #

NCBI: NP_004358.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:250

Western Blot

1:500

Protein

Uniprot #

P51681

Overview

Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.

Molecular Function

G-protein coupled receptor; Transducer; C-C chemokine receptor activity

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes.

Structure

Belongs to the G-protein coupled receptor 1 family.

General Information

Product

CCR6 Antibody

Description

Affinity Purified C-C chemokine receptor type 6 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human C-C chemokine receptor type 6 protein.

Accession #

NCBI:  NP_004358.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:250

Western Blot

1:500

Protein

Uniprot #

P51684

Overview

Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.

Molecular Function

G-protein coupled receptor; Transducer; C-C chemokine receptor activity

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes.

Structure

Belongs to the G-protein coupled receptor 1 family.

Alternative Nomenclature

BN 1 antibody

C C chemokine receptor type 6 antibody

CCR-6 antibody

CD196 antibody

Chemokine (C C motif) receptor 6 antibody

CKR 6 antibody

DRY6 antibody

G protein coupled receptor 29 antibody

GPR-CY4 antibody

LARC receptor antibody

Seven transmembrane receptor lymphocyte 22 antibody

STRL22 antibody

General Information

Product

CXCR2 Antibody

Verified Applications

CM, ELISA, ICC/IF, IHC-Fr, IHC-P, IP, FC, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide:

EDLSNYSYSSTLPPFLLDAAPC

Corresponding to amino acids 18-39 of Human CXCR2.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:250

Western Blot

1:500 Predicted molecular weight: 55 kDa

Protein

Uniprot #

P25025

Overview

Receptor for interleukin-8, binding of IL-8 to the receptor causes the activation of neutrophils.  This response is mediated by a G-protein which activates a phosphatidyinositol-calcium second messenger system.

Molecular Function

G-Protein coupled receptor, Transducer, chemokine receptor activity

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Up-regulated by CREB3

Structure

Binds to HIV-1 Tat and interacts with ARRB1

Alternative Nomenclature

C-X-C chemokine receptor type 2 antibody

CD 182 antibody

CD182 antigen antibody

CDw128b antibody

Chemokine (CXC) receptor 2 antibody

CMKAR2 antibody

CXCR2 antibody

GRO/MGSA receptor antibody

High affinity interleukin-8 receptor B antibody

IL8R B antibody

IL8R2 antibody

IL8RA antibody

Interleukin 8 receptor, beta antibody

Interleukin 8 receptor, type 2 antibody

General Information

Product

CXCR2 Antibody Affinity Purified

Description

Affinity Purified IL8 Receptor beta Antibody C-epitope

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, FC, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

C-epitope Synthetic peptide corresponding to unique amino acid sequences on IL8 Receptor beta protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.60 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:250

Western Blot

1:500

Protein

Uniprot #

P41597

Overview

Receptor for CCL2, CCL7 and CCL13 chemokines.  Transudces a signal via increasing intracellular calcium ion levels.

Molecular Function

G-Protein coupled receptor, Transducer, chemokine receptor activity

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Up-regulated by CREB3

Structure

Binds to HIV-1 Tat and interacts with ARRB1

Alternative Nomenclature

C-X-C chemokine receptor type 2 antibody

CD 182 antibody

CD182 antigen antibody

CDw128b antibody

Chemokine (CXC) receptor 2 antibody

CMKAR2 antibody

CXCR2 antibody

GRO/MGSA receptor antibody

High affinity interleukin-8 receptor B antibody

IL8R B antibody

IL8R2 antibody

IL8RA antibody

Interleukin 8 receptor, beta antibody

Interleukin 8 receptor, type 2 antibody

General Information

Product

CXCR3 Antibody 

Description

Affinity Purified IP10 Receptor Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human CXCR3 protein

Accession #

NCBI:  NP_001495

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.60 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:250

Western Blot

1:500

Protein

Uniprot #

P49682

Molecular Function

G-protein coupled receptor, Transducer, chemokine binding

Subcellular Location

Cell membrane; Multipass membrane protein

Expression

Isoforms 1 and 2 are expressed mainly in the heart, kidney, liver and skeletal muscle.  Isoform 1 is additionally found in placenta, and Isoform 2 is also expressed in endothelial cells.  At protein level, expression is present in T-cells.

Structure

Homomer, forms heteromers with ACKR4

Alternative Nomenclature

C-X-C chemokine receptor type 3 antibody

CD 183 antibody

CD182 antibody

Chemokine CXC Motif Receptor 3 antibody

CKR L2 antibody

CKR-L2 antibody

CMKAR3 antibody

CXC-R3 antibody

G protein-coupled receptor 9 antibody

GPR9 antibody

Interferon-inducible protein 10 receptor antibody

IP-10 receptor antibody

Mig R antibody

Mig receptor antibody

General Information

Product

CXCR3 Antibody Affinity Purified

Description

Affinity Purified IP10 Receptor Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IMM, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 20-70 on rat CXCR3 protein

Accession #

NCBI:  NP_445867.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.60 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:250

Western Blot

1:500

Protein

Uniprot #

QJII9

Overview

Receptor for C-X-C chemokines: CXCL9, CXCCl10 and CXCL11, mediates the proliferation, survival and angiogenic activity of mesangial cells via a heterotrimeric G-protein signalling pathway

Molecular Function

G-Protein coupled receptor, Transducer, chemokine receptor activity

Subcellular Location

Cell membrane; Multipass membrane protein

Structure

Homomer, forms heteromers with ACKR4 by similarity

Alternative Nomenclature

C-X-C chemokine receptor type 3 antibody

CD 183 antibody

CD182 antibody

Chemokine CXC Motif Receptor 3 antibody

CKR L2 antibody

CKR-L2 antibody

CMKAR3 antibody

CXC-R3 antibody

G protein-coupled receptor 9 antibody

GPR9 antibody

Interferon-inducible protein 10 receptor antibody

IP-10 receptor antibody

Mig R antibody

Mig receptor antibody

General Information

Product

CXCR5 Antibody Affinity Purified

Description

Affinity Purified Chemokine (C-X-C motif) receptor 5 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 320-370 on human Chemokine (C-X-C motif) receptor 5 protein.

Accession #

Gen Bank: AAI10353.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

.50-1.20 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q2YD84

Overview

Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.

Molecular Function

B-cell activation.

Subcellular Location

Integral component of plasma membrane; External side of plasma membrane

Expression

Expression in mature B-cells and Burkitt lymphoma cells

Structure

Belongs to the G-protein coupled receptor 1 family

Alternative Nomenclature

BLR 1 antibody

Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5) antibody

C X C chemokine receptor type 5 antibody

CD 185 antibody

Chemokine receptor 5 antibody

CXC chemokine receptor type 5 antibody

CXCR-5 antibody

MDR 15 antibody

MGC117347 antibody

Monocyte-derived receptor 15 antibody

General Information

Product

GPCR GPR15 Antibody

Description

Affinity Purified G-protein coupled receptor 15 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse

Immunogen

Synthetic peptide taken within amino acid region 320-360 on human GPCR GPR15 protein.

Accession #

NCBI: NP_005281

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P49685

Overview

Chemokine receptor; Alternative correceptor with CD4 for HIV-1 infection.

Molecular Function

GPCR; Receptor; Transducer

Subcellular Location

Cell membrane; Multi-pass membrane protein

Structure

Belongs to G-protein coupled receptor 1 family.

Alternative Nomenclature

BOB antibody

Brother of Bonzo antibody

G protein coupled receptor 15 antibody

G protein coupled receptor GPR15 antibody