General Information |
|
Product |
LARP7 Peptide |
Description |
Antigenic Blocking Peptide LARP7 protein Antibody N-epitope |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptide |
Accession # |
GenBank: AAI07710.2 |
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|
Quantity |
250 µg |
Volume |
100 µl |
Determinant |
N-epitope |
Storage |
-20⁰C for long term storage |
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|
Competition/Depletion assay |
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Uniprot # |
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Overview |
Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. |
Molecular Function |
RNA-binding; RNA processing |
Subcellular Location |
Nucleus |
Structure |
Integral part of the 7SK RNP complex. Specifically binds to the highly conserved 3'-terminal U-rich stretch of 7SK RNA. On stimulation, remains associated with 7SK RNA, whereas P-TEFb is released from the complex. |
Alternative Nomenclature |
HDCMA18P antibody La related protein 7 antibody La ribonucleoprotein domain family member 7 antibody P TEFb interaction protein for 7SK stability antibody PIP7S antibody |
Protein information supplied by UniProt
Fabgennix LARP7 Antibody has been used in 2 Publications |
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Adachi, Shungo et al. “ZFP36L1 and ZFP36L2 Control LDLR mRNA Stability via the ERK–RSK Pathway.” Nucleic Acids Research 42.15 (2014): 10037–10049. PMC4150769
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Immunoprecipitation, Western Blot; Human |
Cheng, Yulan et al. “LARP7 Is a Potential Tumor Suppressor Gene in Gastric Cancer.” Laboratory investigation; a journal of technical methods and pathology 92.7 (2012): 1013–1019. PMC3446825
|
Immunoprecipitation, Western Blot; Human |
Publishing research using LARP7-701AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
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LARP7-712AP | |||
|
LARP7.712-FITC | |||
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LARP7.712-BIOTIN | |||
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PC-LARP7 | |||
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