General Information |
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Product |
Phospho-PDE5A Peptide |
Description |
Antigenic Blocking Peptide Phosphorylated Phosphodiesterase 5A |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Phosphorylated synthetic peptide common to all PDE5A variants taken within amino acid region 120-170 on human PDE5A protein. |
Accession # |
GenBank: EAX05277.1 |
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|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
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Competition/Depletion assay |
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Uniprot # |
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Overview |
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP. |
Molecular Function |
Hydrolase, 3',5'-cyclic-GMP phosphodiesterase activity, cGMP binding |
Subcellular Location |
cytosol |
Expression |
Expressed in aortic smooth muscle cells, heart, placenta, skeletal muscle and pancreas and, to a much lesser extent, in brain, liver and lung. |
Alternative Nomenclature |
5''-cyclic phosphodiesterase antibody CGB PDE antibody cGMP binding cGMP specific 3' 5' cyclic nucleotide phosphodiesterase antibody cGMP binding/cGMP specific phosphodiesterase antibody cGMP specific 3'5' cyclic phosphodiesterase antibody cGMP specific phosphodiesterase PDE5A2 antibody cGMP specific phosphodiesterase type 5A antibody cGMP-binding cGMP-specific phosphodiesterase antibody cGMP-specific 3'' antibody CN5A antibody CN5N antibody PDE 5 antibody PDE 5A antibody PDE5A1 antibody Phosphodiesterase 5A antibody Phosphodiesterase 5A cGMP specific antibody Phosphodiesterase isozyme 5 antibody |
Protein information supplied by UniProt
Fabgennix Phospho-PDE5A Antibody has been used in 14 Publications |
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MHerrera, Emilio A., et al. "The role of nitric oxide signaling in pulmonary circulation of highand low-altitude newborn sheep under basal and acute hypoxic conditions." Nitric Oxide, 89, 71-80. PMID: 31063821 |
Western Blot; Sheep |
Musicki, Biljana, et al. "Testosterone replacement in transgenic sickle cell mice controls priapic activity and upregulates PDE5 expression and eNOS activity in the penis." Andrology 6.1 (2018): 184-191. PMID29145710
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Western Blot; Mouse |
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Western Blot; Mouse |
Nino, Paula Katherina Bautista, et al. "Phosphodiesterase 1 regulation is a key mechanism in vascular aging." Clinical Science (2015): CS20140753. PMID26464516 |
Western Blot; Mouse |
Nino, Paula Katherina Bautista, et al. "Phosphodiesterase 1 regulation is a key mechanism in vascular aging." Clinical Science (2015): CS20140753. PMID26464516
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Western Blot; Mouse |
Rajagopal, Senthilkumar, et al. "Cytokine-Induced S-Nitrosylation of Soluble Guanylyl Cyclase and Expression of Phosphodiesterase 1A Contribute to Dysfunction of Longitudinal Smooth Muscle Relaxation." Journal of Pharmacology and Experimental Therapeutics 352.3 (2015): 509-518.PMID25550199
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Western Blot; Mouse |
Click Here for the complete list of all FabGennix Phospho-PDE5A Antibody publications
Publishing research using PPD5A-140AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
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PPD5A-140AP | |||
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PPD5A-FITC | |||
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PPD5A-BIOTIN | |||
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PC-PPD5A | |||
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