General Information |
|
Product |
14-3-3 sigma Peptide |
Description |
Antigenic Blocking Peptide 14-3-3 protein sigma / STRATIFIN / SFN |
Verified Applications |
Immunodepletion, Immunocompetition |
Immunogen |
Synthetic peptide taken within amino acid region 150-220 on human 14-3-3 protein sigma / STRATIFIN / SFN protein. |
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|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
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Competition/Depletion assay |
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Uniprot # |
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Overview |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.1 Publication p53-regulated inhibitor of G2/M progression. |
Molecular Function |
cadherin binding identical protein binding phosphoprotein binding protein domain specific binding protein kinase binding protein kinase C inhibitor activity |
Subcellular Location |
Nucleus, secreted |
Expression |
Present mainly in tissues enriched in stratified squamous keratinizing epithelium. |
Structure |
Belongs to the 14-3-3 family. |
Alternative Nomenclature |
14 3 3 protein sigma antibody 1433S_HUMAN antibody Epithelial cell marker protein 1 antibody Er antibody HME 1 antibody Mkrn3 antibody Mme1 antibody RP23 137L22.11 antibody SFN antibody SFN protein antibody Stratifin antibody YWHAS antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
---|---|---|---|---|
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SFN-101AP | |||
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SFN-BIOTIN | |||
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SFN-FITC | |||
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PC-SFN | |||
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