General Information

Product

TMEM16A Antibody

Description

Affinity Purified Transmembrane protein 16A Antibody N-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region on 70-120 on mouse Transmembrane Protein 16A.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q8BHY3

Overview

Calcium-activated chloride channel (CaCC) which plays an important role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.

Molecular Function

Chloride channel, Developmental protein, Ion channel

Subcellular Location

Cell membrane; Multi-pass membrane protein, Cytoplasm

Expression

Highly expressed in pulmonary bronchiole epithelial cells, pancreatic and submandibular gland acinar cells, kidney proximal tubule, all retinal cell layers, most sensory cells of dorsal root ganglia, Leydig cells and spermatocytes (at protein level). Expressed at high levels in the thyroid gland and gastrointestinal muscles.

Structure

Homodimer. Interacts with CFTR.

Alternative Nomenclature

ANO 1 antibody

Anoctamin 1 antibody

Anoctamin 1 calcium activated chloride channel antibody

Ca2+ activated Cl- channel antibody

Discovered on gastrointestinal stromal tumors protein 1 antibody

DOG 1 antibody

Membrane protein antibody

Oral cancer overexpressed protein 2 antibody

ORAOV 2 antibody

TAOS2 antibody

Transmembrane protein 16A antibody

Tumor-amplified and overexpressed sequence 2 antibody

General Information

Product

TMEM16A Antibody

Description

Affinity Purified Transmembrane protein 16A Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 900-950 on human Transmembrane protein 16A.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q5XXA6

Overview

Calcium-activated chloride channel (CaCC) which plays an important role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.

Molecular Function

Chloride channel, Developmental protein, Ion channel

Subcellular Location

Cell membrane; Multi-pass membrane protein, Cytoplasm

Expression

Highly expressed in pulmonary bronchiole epithelial cells, pancreatic and submandibular gland acinar cells, kidney proximal tubule, all retinal cell layers, most sensory cells of dorsal root ganglia, Leydig cells and spermatocytes (at protein level). Expressed at high levels in the thyroid gland and gastrointestinal muscles.

Structure

Homodimer. Interacts with CFTR (By similarity).

Alternative Nomenclature

ANO 1 antibody

Anoctamin 1 antibody

Anoctamin 1 calcium activated chloride channel antibody

Ca2+ activated Cl- channel antibody

Discovered on gastrointestinal stromal tumors protein 1 antibody

DOG 1 antibody

Membrane protein antibody

Oral cancer overexpressed protein 2 antibody

ORAOV 2 antibody

TAOS2 antibody

Transmembrane protein 16A antibody

Tumor-amplified and overexpressed sequence 2 antibody

General Information

Product

Human Growth Hormone C-epitope

Verified Applications

CM, ELISA, ICC, IHC, IF, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

C-epitope synthetic peptide taken within amino acid region 150-250 on human Growth Hormone beta subunit protein.

Accession #

GenBank: AAA72260

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.77 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

DB

1:50,000

ELISA

1:50,000

Immunocytochemistry

1:250

Immunohistochemistry

1:250

Western Blot

1:500

Protein

Uniprot #

UPI000011EEA5

Overview

Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.

Molecular Function

Metal-binding, Zinc

Subcellular Location

Secreted

Structure

Monomer, dimer, trimer, tetramer and pentamer, disulfide-linked or non-covalently associated, in homopolymeric and heteropolymeric combinations. Can also form a complex either with GHBP or with the alpha2-macroglobulin complex.

Alternative Nomenclature

GH 1 antibody

GH antibody

GH N antibody

Growth Hormone 1 antibody

Growth hormone 1 variant 2 antibody

Growth hormone antibody

Growth Hormone Pituitary antibody

HG1 antibody

HGHN antibody

IGHD1B antibody

Pituitary Growth Hormone antibody

RNGHGP antibody

Somatotropin C antibody

Somatotropin antibody

General Information

Product

Growth Hormone Antibody

Verified Applications

CM, ELISA, ICC, IHC, IF, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-60 on human Growth Hormone beta subunit protein.

Accession #

GenBank: AAA72260

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.77 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

DOT Blot

1:50,000

ELISA

1:5,000 - 1:10,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Western Blot

1:500 - 1:1,000

Protein

Uniprot #

UPI000011EEA5

Overview

Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.

Molecular Function

Metal-binding, Zinc

Subcellular Location

Secreted

Structure

Monomer, dimer, trimer, tetramer and pentamer, disulfide-linked or non-covalently associated, in homopolymeric and heteropolymeric combinations. Can also form a complex either with GHBP or with the alpha2-macroglobulin complex.

Alternative Nomenclature

GH 1 antibody

GH antibody

GH N antibody

Growth Hormone 1 antibody

Growth hormone 1 variant 2 antibody

Growth hormone antibody

Growth Hormone Pituitary antibody

HG1 antibody

HGHN antibody

IGHD1B antibody

Pituitary Growth Hormone antibody

RNGHGP antibody

Somatotropin C antibody

Somatotropin antibody

General Information

Product

ZMPSTE24 Antibody

Description

Affinity Purified CAAX prenyl protease 1 homolog Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Rat, Mouse

Immunogen

Synthetic peptide taken within amino acid region 450-480 on mouse ZMPSTE24 protein.

Accession #

NCBI:  NP_766288

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q80W54

Overview

Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C.

Molecular Function

Metal ion binding

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein; Nucleus inner membrane; Multi-pass membrane protein

Alternative Nomenclature

CAAX prenyl protease 1 homolog antibody

FACE-1 antibody

Farnesylated proteins-converting enzyme 1 antibody

Prenyl protein specific endoprotease 1 antibody

STE24 antibody

Zinc metalloproteinase Ste24 homolog antibody

zmpste24 antibody

General Information

Product

ZMPSTE24 Antibody Affinity Purified

Description

Affinity Purified CAAX prenyl protease 1 homolog Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Rat, Mouse

Immunogen

Synthetic peptide taken within amino acid region 450-480 on mouse ZMPSTE24 protein.

Accession #

NCBI:  NP_766288

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q80W54

Overview

Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C.

Molecular Function

Metal ion binding

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein; Nucleus inner membrane; Multi-pass membrane protein

Alternative Nomenclature

CAAX prenyl protease 1 homolog antibody

FACE-1 antibody

Farnesylated proteins-converting enzyme 1 antibody

Prenyl protein specific endoprotease 1 antibody

STE24 antibody

Zinc metalloproteinase Ste24 homolog antibody

zmpste24 antibody

General Information

Product

Sall4C Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Monkey, Pig

Immunogen

Synthetic peptide taken within amino acid region 226-276 on human SALL4C protein.

Accession #

GenBank: AAO16567.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q6Y8G5

Overview

Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells.

Molecular Function

DNA binding; Metal ion binding; Transcription Regulation

Subcellular Location

Cytoplasm, Nucleus

Structure

Belongs to the sal C2H2-type zinc-finger protein family.

Contains 7 C2H2-type zinc fingers.

Alternative Nomenclature

AA407717 antibody

AL022809 antibody

AW536104 antibody

C330011P20Rik antibody

C78083 antibody

C78563 antibody

DRRS antibody

HSAL4 antibody

Sal-like Protein 4 antibody

Spalt like transcription factor 4 antibody

Tex20 antibody

Zinc finger protein 797 antibody

Zinc finger protein SALL4 antibody

ZNF797 antibody

General Information

Product

Sall4C Antibody

Description

Affinity Purified SALL4C Antibody N-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Monkey, Mouse, Pig, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human SALL4C protein.

Accession #

GenBank: AAO16567.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q6Y8G5

Overview

Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells.

Molecular Function

DNA binding; Metal ion binding; Transcription Regulation

Subcellular Location

Cytoplasm, Nucleus

Structure

Belongs to the sal C2H2-type zinc-finger protein family.

Contains 7 C2H2-type zinc fingers.

Alternative Nomenclature

AA407717 antibody

AL022809 antibody

AW536104 antibody

C330011P20Rik antibody

C78083 antibody

C78563 antibody

DRRS antibody

HSAL4 antibody

Sal-like Protein 4 antibody

Spalt like transcription factor 4 antibody

Tex20 antibody

Zinc finger protein 797 antibody

Zinc finger protein SALL4 antibody

ZNF797 antibody