General Information |
|
Product |
ASXL1 Antibody |
Description |
Affinity Purified Putative Polycomb group protein ASXL1 Antibody |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 1120-1180 on mouse Putative Polycomb group protein ASXL1. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5-1.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
Affinity Purified |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20?C for long term storage |
|
|
ELISA |
1:50,000 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500-1:5,000 |
|
|
Uniprot # |
|
Overview |
Probable Polycomb group (PcG) protein involved in transcriptional regulation mediated by ligand-bound retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG) (PubMed:16606617). Acts as a coactivator of RARA and RXRA through association with NCOA1 (PubMed:16606617). Acts as a corepressor for PPARG and suppresses its adipocyte differentiation-inducing activity (PubMed:21047783). |
Molecular Function |
chromatin binding DNA binding metal ion binding peroxisome proliferator activated receptor binding retinoic acid receptor binding transcription coactivator activity |
Subcellular Location |
Nucleus |
Structure |
Belongs to the Asx family. |
Alternative Nomenclature |
Additional sex combs like 1 (Drosophila) antibody Additional sex combs like protein 1 antibody ASXL1 antibody ASXL1_HUMAN antibody KIAA0978 antibody Putative Polycomb group protein ASXL1 antibody |
Protein information supplied by UniProt.
ASXL2-201AP
|
ASXL3-301AP
|
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