General Information
|
|
Product
|
Aquaporin 1 Antibody FITC-Conjugated
|
Verified Applications
|
ELISA, ICC, IF, IHC, IP, WB
|
Host
|
Rabbit
|
Species Cross Reactivity
|
Bovine, Human, Sheep, Mouse, Rat
|
Immunogen
|
Synthetic peptide taken within amino acid region 215-265 on human Aquaporin 1 protein.
|
Accession #
|
GenBank: AAL87136
|
Physical Properties
|
|
Quantity
|
100 µg
|
Volume
|
200 µl
|
Concentration
|
0.55-0.59 µg/µl in antibody stabilization buffer
|
Immunoglobulin
|
IgG
|
Form
|
FITC-Conjugated
|
Clonality
|
Polyclonal
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
ELISA
|
1:10,000
|
Immunocytochemistry
|
1:100
|
Immunofluorescence
|
1:100
|
Immunohistochemistry
|
1:100
|
Immunoprecipitation
|
1:200
|
Western Blot
|
1:500
|
Protein
|
Uniprot #
|
P29972
|
Overview
|
Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
|
Molecular Function
|
Blood group antigen; Transport
|
Subcellular Location
|
Cell membrane; Multi-pass membrane protein
|
Expression
|
Detected in erythrocytes (at protein level). Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver.
|
Structure
|
Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
|
Alternative Nomenclature
|
AQP 1 antibody
AQP CHIP antibody
aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group) antibody
Aquaporin CHIP antibody
Aquaporin-1 antibody
Channel forming integral protein 28kDa antibody
Channel like integral membrane protein 28 kDa antibody
CHIP 28 antibody
CO antibody
Colton blood group antibody
Growth factor induced delayed early response protein antibody
MGC26324 antibody
Urine water channel antibody
Water channel protein CHIP 29 antibody
Water channel protein for red blood cells and kidney proximal tubule antibody
|
|
|