General Information
|
|
Product
|
C6orf150 Peptide
|
Description
|
Antigenic Blocking Peptide Cyclic GMP-AMP synthase Antibody N-epitope
|
Verified Applications
|
Immunodepletion/Immunocompetition Assay
|
Peptide Description
|
Synthetic peptide taken within amino acid regions 350-450 on human cGAS protein.
|
Accession #
|
NCBI: NP_612450
|
Physical Properties
|
|
Quantity
|
250 µg
|
Volume
|
100 µl
|
Form
|
Antigenic Blocking Peptide
|
Determinant
|
N-epitope
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
Competition/Depletion assay
|
Refer to competition assay protocol
|
Protein
|
Uniprot #
|
Q8N884
|
Overview
|
Catalyzes the formation of cyclic GMP-AMP from ATP and GTP. Has antiviral activity through acting as a cystolic DNA senser.
|
Molecular Function
|
Nucleotidyltransferase; ATP binding; DNA binding
|
Subcellular Location
|
Cytoplasm; Cytosol
|
Expression
|
Is expressed in the monocytic cell line THP1 by type 1 Interferons
|
Structure
|
Monomer when in absence of DNA. Homodimer when bound to DNA.
|
Alternative Nomenclature
|
C6orf150 antibody
cGAMP synthase antibody
cGAS antibody
Chromosome 6 open reading frame 150 antibody
Cyclic GMP-AMP synthase antibody
h-cGAS antibody
Hypothetical protein LOC115004 antibody
Mab 21 domain containing 1 antibody
MB21D1 antibody
protein MB21D1 antibody
Uncharacterized protein C6orf150 antibody
|
|
|