General Information |
|
Product |
AMPK alpha 1 Peptide |
Description |
Antigenic Blocking Peptide 5'-AMP-activated protein kinase catalytic subunit alpha-1 |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptide taken within amino acid region 500-550 on rat 5'-AMP-activated protein kinase catalytic subunit alpha-1 protein. |
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|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
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Competition/Depletion assay |
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Uniprot # |
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Overview |
Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. |
Molecular Function |
[acetyl-CoA carboxylase] kinase activity [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity AMP-activated protein kinase activity ATP binding chromatin binding |
Subcellular Location |
Nucleus, Cytoplasm |
Expression |
Low expression in kidney, liver, lung, heart and brain. |
Structure |
The AIS (autoinhibitory sequence) region shows some sequence similarity with the ubiquitin-associated domains and represses kinase activity. |
Alternative Nomenclature |
5 AMP activated protein kinase alpha 1catalytic subunit antibody AAPK1 antibody ACACA kinase antibody acetyl CoA carboxylase kinase antibody AMP -activate kinase alpha 1 subunit antibody AMPK 1 antibody AMPK alpha 1 antibody HMG CoA reductase kinase antibody HMGCR kinase antibody hormone sensitive lipase kinase antibody Hydroxymethylglutaryl CoA reductase kinase antibody im:7154392 antibody kinase AMPK alpha1 antibody PRKAA 1 antibody Protein kinase AMP activated alpha 1 catalytic subunit antibody SNF1A antibody Tau protein kinase PRKAA1 antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
---|---|---|---|---|
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AMPK1-101AP | |||
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AMPK1-BIOTIN | |||
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AMPK1-FITC | |||
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