General Information |
|
Product |
Soluble Adenylate Cyclase 10 Antibody BIOTIN-Conjugated |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Gorilla |
Immunogen |
Synthetic peptide taken within amino acid region 200-250 on mouse Adenylate Cyclase type 10 protein. |
Accession # |
NCBI: NP_766617.2 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.55-0.75 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunoprecipitation |
1:150 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. |
Molecular Function |
Adenylate cyclase activity; ATP binding; Magnesium ion binding; Manganese ion binding |
Subcellular Location |
Cell membrane, Cytoplasm, Cytoskeleton, Membrane |
Expression |
Expressed in testis. |
Structure |
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Contains 2 guanylate cyclase domains. |
Alternative Nomenclature |
3',5'-cyclic AMP synthetase antibody Adenylate cyclase 10 (soluble) antibody AH related protein antibody ATP pyrophosphate-lyase antibody Germ cell soluble adenylyl cyclase antibody HCA2 antibody hsAC antibody hypercalciuria absorptive antibody SAC antibody SACI antibody Sacy antibody Soluble adenylyl cyclase antibody Testicular soluble adenylyl cyclase antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-SAC10 | |||
|
SAC10-101AP | |||
|
SAC10-FITC | |||
|
PC-SAC10 | |||
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