General Information |
|
Product |
ITPR2 Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Inositol 1,4,5-triphosphate receptor type 2 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 100-150 on rat Inosital 1,4,5-triphosphate receptor type 2 protein. |
Accession # |
NCBI: NP_112308 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.66 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunohistochemistry | 1:50-1:100 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA. |
Molecular Function |
Calcium ion binding; inositol 1,4,5-triphosphate binding; cellular response to hypoxia; Transport |
Subcellular Location |
Endoplasmic reticulum membrane; Multi-pass membrane protein |
Expression |
Isoform Short is found in skeletal muscle and heart. |
Structure |
The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region. |
Alternative Nomenclature |
4 antibody 5-trisphosphate receptor antibody Inositol 1 4 5 trisphosphate receptor type 2 antibody InsP3R2 antibody IP3 R2 antibody IP3 receptor antibody IP3 receptor isoform 2 antibody IP3R 2 antibody ITPR 2 antibody Type 2 inositol 1 4 5 trisphosphate receptor antibody Type 2 inositol 1 antibody Type 2 InsP3 receptor antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-ITPR2 | |||
|
ITPR2-201AP | |||
|
ITPR2-FITC | |||
|
PC-ITPR2 | |||
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