General Information
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Product
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Synaptophysin Antibody FITC-Conjugated C-epitope
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Verified Applications
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CM, ELISA, ICC, IF, IHC, IMM, WB
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Host
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Rabbit
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Species Cross Reactivity
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Chicken, Human, Monkey, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 250-350 on human Synaptophysin protein.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.60-0.62 µg/µl in antibody stabilization buffer
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Determinant
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C-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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Confocal Microscopy
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1:100
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DB
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1:10,000
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ELISA
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1:10,000
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Immunocytochemistry
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1:100
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Immunofluorescence
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1:100
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Immunohistochemistry
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1:100
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Immunoprecipitation
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1:125
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Western Blot
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1:1,000
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Protein
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Uniprot #
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P08247
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Overview
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Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).
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Molecular Function
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Cholesterol binding, protein self-association, transporter activity
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Subcellular Location
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Cytoplasmic vesicle › secretory vesicle › synaptic vesicle membrane; Multi-pass membrane protein. Cell junction ›synapse › synaptosome
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Expression
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Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
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Structure
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Homohexamer or homotetramer. Interacts with SRCIN1.
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Alternative Nomenclature
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Major synaptic vesicle protein P38 antibody
MRXSYP antibody
Syn p38 antibody
Synaptophysin antibody
SYP antibody
SYPH antibody
SypI antibody
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