General Information |
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Product |
DYRK2 Positive Control |
Description |
Western Blot Positive Control Dual specificity tyrosine-phosphorylation-regulated kinase 2 Antibody |
Verified Applications |
WB |
Immunogen |
Purified protein |
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|
Quantity |
5 Applications |
Volume |
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Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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Western Blot |
1:500 |
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Uniprot # |
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Overview |
Serine/threonine-protein kinase involved in the regulation of the mitotic cell cycle, cell proliferation, apoptosis, organization of the cytoskeleton and neurite outgrowth. Functions in part via its role in ubiquitin-dependent proteasomal protein degradation. Functions downstream of ATM and phosphorylates p53/TP53 at 'Ser-46', and thereby contributes to the induction of apoptosis in response to DNA damage. Phosphorylates NFATC1, and thereby inhibits its accumulation in the nucleus and its transcription factor activity. |
Molecular Function |
Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase |
Subcellular Location |
Cytoplasm, Nucleus |
Expression |
Testis, after the onset of spermatogenesis. |
Structure |
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily. Contains 1 protein kinase domain. |
Alternative Nomenclature |
AOMS3 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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DYRK2-201AP | |||
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DYRK2-BIOTIN | |||
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DYRK2-FITC | |||
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P-DYRK2 | |||
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