General Information
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Product
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PELO Antibody FITC-Conjugated
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Description
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FITC-Conjugated PELOTA Antibody
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Verified Applications
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DB, ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 330-380 on human PELOTA protein.
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Accession #
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GenBank: AAG22575.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.68-0.70 µg/µl in antibody stabilization buffer
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:4,000
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ELISA
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1:4,000
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Immunohistochemistry |
1:50-1:100 |
Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9BRX2
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Overview
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Is necessary in cell division for normal chromosome segregation and genomic stability. It may recognize stalled ribosomes and trigger endonucleolytic cleavage of the mRNA, and may have ribonuclease activity.
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Molecular Function
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Endonuclease, Hydrolase, Nuclease
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Subcellular Location
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Nuclease, Cytoplasm
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Expression
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Expressed ubiquitously
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Structure
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The N-terminal domain has the RNA-binding Sm fold. It may harbor the endoribonuclease activity (Potential). Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
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Alternative Nomenclature
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CGI 17 antibody
pelo antibody
pelota (Drosophila) homolog antibody
pelota homolog antibody
PRO1770 antibody
Protein pelota homolog antibody
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