General Information |
|
Product |
Src Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Proto-oncogene tyrosine-protein kinase Src Antibody C-epitope |
Verified Applications |
CM, ELISA, IF, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 400-500 on human Src protein. |
Accession # |
NCBI: NP_005408.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.56-0.60 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Determinant |
C-epitope |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:10,000 |
Immunocytochemistry |
1:100 |
Immunofluorescence |
1:100 |
Immunohistochemistry |
1:100 |
Immunoprecipitation |
1:250 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis migration, and transformation. |
Molecular Function |
ATP binding, ephrin receptor binding, heme binding, ion channel binding, enzyme binding, growth factor receptor binding, integrin binding, kinase activity |
Subcellular Location |
Cell membrane, mitochondrion inner membrane, nucleus, cytoplasm (Note: Localizes to focal adhesion sites following integrin engagement. Localization to focal adhesion sites requires myristoylation and SH3 domain.) |
Expression |
Expressed ubiquitously. Platelets, neurons and osteoclasts express 5-fold to 200-fold higher levels than most other tissues. |
Structure |
Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. Contains 1 protein kinase domain. Contains 1 SH2 domain. Contains 1 SH3 domain. |
Alternative Nomenclature |
ASV antibody Avian sarcoma virus antibody c SRC antibody CDNA FLJ14219 fis clone NT2RP3003800 highly similar to Rattus norvegicus tyrosine protein kinase pp60 c src mRNA antibody cSrc antibody EC 2.7.10.2 antibody Neuronal CSRC tyrosine specific protein kinase antibody Neuronal SRC antibody Oncogene SRC antibody p60 Src antibody Proto oncogene tyrosine protein kinase Src antibody Protooncogene SRC antibody protooncogene SRC Rous sarcoma antibody Src antibody SRC Oncogene antibody SRC proto oncogene non receptor tyrosine kinase antibody SRC1 antibody Tyrosine kinase pp60c src antibody Tyrosine protein kinase SRC 1 antibody v src avian sarcoma (Schmidt Ruppin A2) viral oncogene homolog antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-Src.112 | |||
|
Src-112AP | |||
|
Src.112-FITC | |||
|
PC-SRC | |||
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