General Information
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Product
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TPCN2 Antibody
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Description
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Affinity Purified Two pore calcium channel protein 2 Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human
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Immunogen
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Synthetic peptide taken within amino acid region 205-255 on human TPC2 protein.
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Accession #
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NCBI: NP_620714.2
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.57 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation |
1:200 |
Western Blot
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1:500
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Protein
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Uniprot #
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Q8NHX9
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Overview
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Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca2+ channels (VDCC) across the lysosomal membrane. May be involved in smooth muscle contraction.
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Molecular Function
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Calcium channel, Ion channel, Voltage-gated channel
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Subcellular Location
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Lysosome membrane; Multi-pass membrane protein
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Expression
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Widely expressed. Expressed at high level in liver and kidney.
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Structure
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Homodimer. Interacts with LRRK2.
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Alternative Nomenclature
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SHEP10 antibody
TPC2 antibody
Two pore calcium channel protein 2 antibody
Voltage dependent calcium channel protein TPC2 antibody
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