General Information |
|
Product |
SIRT7 Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Sirtuin 7 Antibody C-epitope |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 350-400 on mouse SIRT7 protein. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.50 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Determinant |
C-epitope |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
NAD-dependent protein deacetylase that specifially mediates deacetylation of histone H3 at 'Lys-18'. Displays selectivity for a single histone mark, H3K18Ac, directly linked to control of gene expression. |
Molecular Function |
Chromatin binding, NAD+ binding, NAD-dependent histone deacetylase activity (H3-K18 specific), metal ion binding |
Subcellular Location |
Cytoplasm, nucleus, nucleolus. (Note: Located close to the nuclear membrane when in cytoplasm. Associated with chromatin. Associated with rDNA promoter and transcribed region. Associated with nucleolar organizer regions during mitosis. |
Expression |
Detected in liver, spleen and testis. Detected in embryos. |
Structure |
Belongs to the Sirtuin Family. Class IV subfamily. Contains 1 deacetylase sirtuin-type domain. |
Alternative Nomenclature |
NAD dependent deacetylase sirtuin 7 antibody Regulatory protein SIR2 homolog 7 antibody Silent mating type information regulation 2 homolog antibody SIR2 L7 antibody SIR2 like protein 7 antibody Sir2 related protein type 7 antibody SIRT7 antibody Sirtuin 7 antibody Sirtuin type 7 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-SIRT7.712 | |||
|
SIRT7-712AP | |||
|
SIRT7.712-FITC | |||
|
PC-SIRT7 | |||
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