General Information
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Product
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Phospho-PARP1 Antibody FITC
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Description
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Affinity Purified Phospho-specific Poly ADP-ribose polymerase 1 Antibody FITC
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 870-920 on human Phospho-specific Poly ADP-ribose polymerase 1 protein.
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Accession #
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NCBI: NP_001609
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.58 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunohistochemistry |
1:50-1:100 |
Immunoprecipitation |
1:200 |
Western Blot
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1:500
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Protein
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Uniprot #
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P09874
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Overview
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Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. Mediates glutamate, aspartate, serine, histidine or tyrosine ADP-ribosylation of proteins.
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Molecular Function
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Allosteric enzyme, DNA-binding, Glycosyltransferase, Nucleotidyltransferase, Transferase
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Expression
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Expressed in ventricular zone and 212 other cell types or tissues.
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Structure
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Homodimer; PARP-type zinc-fingers from separate PARP1 molecules form a dimer module that specifically recognizes DNA strand breaks.
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Alternative Nomenclature
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ADP-ribosyltransferase diphtheria toxin-like 1
DNA ADP-ribosyltransferase PARP1
Protein poly-ADP-ribosyltransferase PARP1
PARP1
ADPRT
PPOL
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