General Information |
|
Product |
CD86 Antibody FITC-Conjugated |
Description |
FITC-Conjugated T-lymphocyte activation antigen CD86 isoform 1 precursor Antibody |
Verified Applications |
ELISA, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human |
Immunogen |
Synthetic peptide taken within amino acid region 250-329 on human CD86 protein. |
Accession # |
NCBI: NP_787058 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.50-0.75 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:20,000 |
ELISA |
1:20,000 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. |
Molecular Function |
Receptor; Adaptive Immunity; Host-virus interaction; Immunity |
Subcellular Location |
Cell membrane; Single-pass type I membrane protein |
Expression |
Expressed by activated B-lymphocytes and monocytes. |
Structure |
Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
Alternative Nomenclature |
Activation B7 2 antigen antibody B-lymphocyte activation antigen B7-2 antibody B7 2 antibody B70 antibody BU63 antibody CD 86 antibody CD28 antigen ligand 2 2 antibody CLS1 antibody CTLA 4 counter receptor B7 2 antibody Early T-cell costimulatory molecule 1 antibody ETC-1 antibody FUN 1 antibody LAB72 antibody Ly-58 antibody MB7-2 antibody Membrane glycoprotein antibody MGC34413 antibody T-lymphocyte activation antigen CD86 antibody TS/A-2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
CD86-101AP | |||
|
P-CD86 | |||
|
CD86-BIOTIN | |||
|
PC-CD86 | |||
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