Ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitnase funcitons. Participates in immune and inflammatory responses signaled by cytokines such as TNF-alpha and IL-1 beta or Toll-like receptors through terminating NF-kappa-B activity.
Molecular Function
Hydrolase, Ligas, Protease, Thiol protease
Subcellular Location
Cytoplasm; Nucleus; Lysosome
Expression
Induced by TNF
Structure
Homodimer
Alternative Nomenclature
A20 antibody
OTU domain containing protein 7C antibody
OTUD7C antibody
Putative DNA binding protein A20 antibody
TNAP3_HUMAN antibody
TNF alpha-induced protein 3 antibody
TNFA1P2 antibody
TNFAIP 3 antibody
Tumor necrosis factor alpha induced protein 3 antibody
Tumor necrosis factor inducible protein A20 antibody