General Information
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Product
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PDE7A Antibody
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Description
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Affinity Purified High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A Antibody
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Verified Applications
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ELISA, ICC, IF, IHC, IP, WB
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Host
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Goat
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic cyclic peptide common to all PDE7A variants
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Specificity |
This antibody is specific for PDE7A variants and will not cross-react with PDE7B or other PDE family members. |
Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.50-0.75 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation
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1:250
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Western Blot
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1:500
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Protein
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Uniprot #
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P70453
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Overview
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Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction.
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Molecular Function
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Hydrolase, 3', 5' -cyclic-AMP phosphodiesterase activity
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Expression
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Widely expressed with highest levels in the skeletal muscle.
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Structure
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Interacts with CBFA2T3.
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Alternative Nomenclature
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HCP 1 antibody
P2A antibody
PDE 7 antibody
PDE1/PDE2 yeast human complement of antibody
PDE7A antibody
Phosphodiesterase 7A antibody
Phosphodiesterase isozyme 7 antibody
Rolipram insensitive phosphodiesterase type 7 antibody
TM 22 antibody
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