General Information |
|
Product |
LILRB3 Antibody BIOTIN-Conjugated |
Description |
BIOTIN-Conjugated Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Monkey |
Immunogen |
Synthetic peptide taken within amino acid region 580-631 on human LILRB3 protein. |
Specificity | This antibody will detect all three isoforms of human LILRB3 protein. |
Accession # |
NCBI: NP_001074919.2 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.74 µg/µl in antibody stabilization buffer |
Form |
BIOTIN-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:20,000 |
ELISA |
1:20,000 |
Immunohistochemistry | 1:50-1:150 |
Immunoprecipitation | 1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM). |
Molecular Function |
Receptor, Receptor activity, transmembrane signaling receptor activity |
Subcellular Location |
Cell membrane; Single-pass type I membrane protein |
Expression |
Detected in monocytes and B-cells |
Alternative Nomenclature |
CD85 antigen like family member A antibody HL9 antibody IL T5 antibody Immunoglobulin like transcript 5 antibody LIR 3 antibody MGC138403 antibody Monocyte inhibitory receptor HL9 antibody PIRB antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
P-LILRB3.2 | |||
|
LILRB3-312AP | |||
|
LILRB3.2-FITC | |||
|
PC-LILRB3 | |||
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