General Information |
|
Product |
CXCR2 Antibody FITC-Conjugated |
Verified Applications |
CM, ELISA, ICC/IF, IHC-Fr, IHC-P, IP, FC, |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide:
EDLSNYSYSSTLPPFLLDAAPC
Corresponding to amino acids 18-39 of Human CXCR2. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.50-0.60 µg/µl in antibody stabilization buffer |
Conjugation |
FITC. Ex: 493 nm, Em: 528 nm |
Clonality |
Polyclonal |
Determinant |
N-epitope |
Storage |
-20⁰C for long term storage |
|
|
Confocal Microscopy |
1:200 |
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunocytochemistry |
1:200 |
Immunofluorescence |
1:200 |
Immunohistochemistry |
1:200 |
Immunoprecipitation |
1:250 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Receptor for interleukin-8, binding of IL-8 to the receptor causes the activation of neutrophils. This response is mediated by a G-protein which activates a phosphatidyinositol-calcium second messenger system. |
Molecular Function |
G-Protein coupled receptor, Transducer, chemokine receptor activity |
Subcellular Location |
Cell membrane; Multi-pass membrane protein |
Expression |
Up-regulated by CREB3 |
Structure |
Binds to HIV-1 Tat and interacts with ARRB1 |
Alternative Nomenclature |
C-X-C chemokine receptor type 2 antibody CD 182 antibody CD182 antigen antibody CDw128b antibody Chemokine (CXC) receptor 2 antibody CMKAR2 antibody CXCR2 antibody GRO/MGSA receptor antibody High affinity interleukin-8 receptor B antibody IL8R B antibody IL8R2 antibody IL8RA antibody Interleukin 8 receptor, beta antibody Interleukin 8 receptor, type 2 antibody |
Protein information supplied by UniProt
Fabgennix CXCR2 Antibody has been used in 2 Publications |
|
Sun, Jia, Raina Devi Ramnath, and Madhav Bhatia. "Neuropeptide substance P upregulates chemokine and chemokine receptor expression in primary mouse neutrophils." American Journal of Physiology-Cell Physiology 293.2 (2007): C696-C704. PMID17494633
|
Flow Cytometry; Mouse |
Zhang, Huili, et al. "Endogenous hydrogen sulfide regulates leukocyte trafficking in cecal ligation and puncture-induced sepsis." Journal of leukocyte biology 82.4 (2007): 894-905.
|
Flow Cytometry; Mouse |
Publishing research using CXCR2-201AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
|
CXCR2-201AP | |||
|
P-CXCR20 | |||
|
CXCR20-BIOTIN | |||
|
PC-CXCR2 | |||
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(c) FabGennix International Inc.