General Information |
|
Product |
TLR9 Positive Control |
Description |
Western Blot Positive Control Toll-like receptor 9 |
Verified Applications |
WB |
Immunogen |
Purified Protein |
Accession # |
GenBank: AAQ89443.1 |
|
|
Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
|
|
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. |
Molecular Function |
Receptor, Interleukin-1 receptor binding, siRNA binding |
Subcellular Location |
Endoplasmic reticulum membrane; Single-pass type 1 membrane protein, Endosome, Lysosome, Cytoplasmic vesicle |
Expression |
Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre-dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver. |
Structure |
Interacts with MYD88 via their respective TIR domains (By similarity). Interacts (via transmembrane domain) with UNC93B1 (By similarity). Interacts with CD300LH; the interaction may promote full activation of TLR9-triggered innate responses (By similarity |
Alternative Nomenclature |
CD 289 antibody TLR 9 antibody Toll like receptor 9 isoform A precursor antibody Toll like receptor 9 isoform B antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
TLR-901AP | |||
|
TLR9-FITC | |||
|
P-TLR9 | |||
|
TLR9-BIOTIN | |||
Display accessory details |
Select your currency:
(c) FabGennix International Inc.