General Information |
|
Product |
SLC26A3 Antibody |
Description |
Affinity Purified Chloride anion exchanger Antibody |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide corresponding to amino acids within region 650-700 on human SCL26A3 protein. |
|
|
Quantity |
100 ug |
Concentration |
0.5-1.5 ᄉg/ᄉl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Conjugate |
Unconjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Determinant |
C-epitope |
Storage |
-20ᄀC for long term storage |
|
|
ELISA |
1:10,000 |
Immunocytochemistry |
1:50-1:100 |
Immunofluorescence |
1:50-1:100 |
Immunohistochemistry |
1:50-1:100 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Chloride/bicarbonate exchanger. Mediates the efficient absorption of chloride ions in the colon, participating in fluid homeostasis. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. |
Subcellular Location |
Plasma membrane |
Expression |
Expression is significantly decreased in adenomas (polyps) and adenocarcinomas of the colon. |
Structure |
Transmembrane, Transmembrane helix |
Alternative Nomenclature |
Solute Carrier Family 26 Member 3 DRA Solute Carrier Family 26 (Anion Exchanger), Member 3 Chloride Anion Exchanger CLD Solute Carrier Family 26, Member 3 Down-Regulated In Adenoma Protein Congenital Chloride Diarrhea Down-Regulated In Adenoma Protein DRA |
Protein information supplied by UniProt.
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