General Information

Product

Glucose Transporter GLUT1 Antibody

Verified Applications

ELISA, ICC/IF, IHC-FoFr, IHC-Fr, IHC-P, IP, WB, Immunomicroscopy

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide conjugated to KLH, corresponding to amino acids 478-492 of Human Glucose Transporter GLUT1. Peptide was covalently modified.

Sequence:

PEELFHPLGADSQV

Accession #

GenBank: AAC28635.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:12,000

Immunocytochemistry

1:50-1:200

Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Immunoprecipitation

1:200

Western Blot

1:5,000

Protein

Uniprot #

P11166

Overview

Facilitative glucose transporter.  May be responsible for constitutive or basal glucose uptake.

Molecular Function

Sugar Transport

Subcellular Location

Cell membrane; Multi-pass membrane protein; melanosome

Expression

Detected in erythrocytes.  Variable expression in many human tissues

Structure

Transmembrane helix

Alternative Nomenclature

DYT17 antibody

DYT18 antibody

erythrocyte/brain antibody

Erythrocyte/brain HepG2 glucose transporter antibody

Erythrocyte/hepatoma glucose transporter antibody

facilitated glucose transporter member 1 antibody

Glucose transporter 1 antibody

GLUT1 antibody

GLUT1DS antibody

GLUTB antibody

GT1 antibody

GTG1 antibody

Gtg3 antibody

GTR1_HUMAN antibody

HepG2 glucose transporter antibody

PED antibody

RATGTG1 antibody

SLC2A1 antibody

Solute carrier family 2 (facilitated glucose transporter), member 1 antibody

General Information

Product

Glucose Transporter GLUT10 Antibody 

Description

Affinity Purified Solute carrier family 2 (facilitated glucose transporter), member 10 Antibody

Verified Applications

ELISA, ICC/IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within C-terminal region, amino acids 500-536 of rat Glucose Transporter GLUT10 protein. Peptide was covalently modified and coupled to a carrier protein.

Accession #

NCBI:  EDL96452.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.54 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:100

DB

1:4,500

ELISA

1:4,500

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

UPI000155277B

Overview

Facilitative glucose transporter

Molecular Function

Sugar transport, Transport

Subcellular Location

Endomembranesystem; Multi-pass membrane protein; perinuclear region

Expression

Widely expressed; highest levels in liver and pancreas.

Structure

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Alternative Nomenclature

AA450473 antibody

facilitated glucose transporter member 10 antibody

Glucose transporter type 10 antibody

glut 10 antibody

MGC126706 antibody

SLC2A10 antibody

Solute carrier family 2 antibody

General Information

Product

GLUT12 Antibody

Description

Affinity Purified Solute carrier family 2 facilitated glucose transporter member 12 Antibody

Verified Applications

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide from the C-terminus of Rat GLUT12. 

Accession #

GenBank: EDL87731.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Dot Blot

1:4500

ELISA

1:4500

Immunoprecipitation

1:200

Western Blot

1:500. Predicted molecular weight 67 kDa.

Protein

Uniprot #

D3ZNG4

Overview

Substrate-specific transmembrane transporter activity

Molecular Function

Sugar Transport

Subcellular Location

Integral component of membrane

Structure

Belongs to major facilitator superfamily Sugart Transporter family.

Alternative Nomenclature

Glucose transporter type 12 antibody

GLUT8 antibody

SLC2A12 antibody

Solute carrier family 2 (facilitated glucose transporter) member 12 antibody

General Information

Product

Glucose Transporter GLUT7 Antibody 

Description

Affinity Purified Solute carrier family 2, facilitated glucose transporter member 7 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on rat GLUT7 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,500

ELISA

1:4,500

Immunoprecipitation

1:200

Western Blot

1:500-1:750

Protein

Overview

High-affinity transporter for glucose and fructose Does not transport galactose, 2-deoxy-d-glucose and xylose.

Molecular Function

substrate-specific transmembrane transporter activity

Subcellular Location

Membrane; Multi-pass membrane protein

Expression

Expressed in small intestine and colon. Weakly expressed in testis and prostate.

Alternative Nomenclature

facilitated glucose transporter member 7 antibody

Glucose transporter type 7 antibody

GLUT7 antibody

Intestinal facilitative glucose transporter 7 antibody

RP5-963K15.3 antibody

SLC2A7 antibody

Solute carrier family 2 (facilitated glucose transporter), member 7 antibody

Solute carrier family 2 antibody

General Information

Product

Glucose Transporter 8 Antibody Affinity Purified

Description

Affinity Purified Solute carrier family 2, facilitated glucose transporter member 8 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse , Rat

Immunogen

Synthetic peptide taken within amino acid region 400-500 on GLUT8 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.56-0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9NY64

Overview

Insulin-regulated facilitative glucose transporter.  Binds cytochalasin B in glucose-inhibitable manner.

Molecular Function

Sugar Transport

Subcellular Location

Cell membrane; Multi-pass membrane protein; Cytoplasmic vessicle membrane

Expression

Highly expressed in testis; lower amounts in other tissues.  Down regulated by estrogen.

Structure

Interacts with AP2B1

Alternative Nomenclature

Glucose transporter type 8 antibody

Glucose transporter type X1 antibody

GLUT8 antibody

GLUTX1 antibody

solute carrier family 2 (facilitated glucose transporter) member 8 antibody

General Information

Product

Glucose Transporter 9 Antibody Affinity Purified

Description

Affinity Purified Solute carrier family 2, facilitated glucose transporter member 9 Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 50-570 on Glut 9 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,500

ELISA

1:4,500

Immunoprecipitation

1:200

Western Blot

1:500-1:750

Protein

Uniprot #

Q9NRM0

Overview

Urate and fructose transport.  Also transports glucose at lower rate.

Molecular Function

Sugar Transport

Subcellular Location

Membrane; Multi-pass membrane

Expression

Basolateral membranes of proximal renal tubular cells, liver and placenta.  Also found in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articiular cartilage.

Structure

Transmembrane helix

Alternative Nomenclature

glucose transporter 9 antibody

GLUT9 antibody

GLUTX antibody

Human glucose transporter like protein 9 antibody

SLC2A9 antibody

Solute carrier family 2, facilitated glucose transporter member 9 antibody

UAQTL2 antibody

Urate voltage driven efflux transporter 1 antibody

URATv1 antibody

General Information

Product

SLC12A1 Antibody Affinity Purified

Description

Affinity Purified NKCC2 variant A Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 30-60 on NKCC2 protein.

Accession #

GenBank: ABU63482.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

A8JYG7

Molecular Function

cation:chloride symporter activity

Subcellular Location

integral component of membrane

Alternative Nomenclature

BSC1 antibody

Bumetanide sensitive sodium 3 antibody

Kidney-specific Na-K-Cl symporter antibody

MGC48843 antibody

NKCC2 antibody

potassiumchloride cotransporter 2 antibody

Slc12a1 antibody

sodium potassium chloride cotransporter 2 antibody

solute carrier family 12

General Information

Product

Niemann Pick C1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1228-1278 on human Niemann-Pick C1 protein.

Accession #

NCBI:  NP_000262.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:4,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

O15118

Overview

Intracellular cholesterol transporter plays an important role in the egress of cholesterol from the endosomal/lysosomal compartment.

Molecular Function

Receptor activity

Subcellular Location

Endosome, Lysosome, Membrane

Expression

Adrenal gland; Cerebral cortex; lung; placenta; lymph node

Structure

Belongs to the patched family.

Alternative Nomenclature

Niemann Pick C1 antibody

Niemann Pick C1 protein precursor antibody

Niemann Pick disease, type C1 antibody

NPC antibody

NPC1 antibody

General Information

Product

P2Y12 Antibody

Description

P2Y purinoceptor 12 Antibody

Verified Applications

Cell labeling, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Chimpanzee, Human, Monkey, Porcine, Rat

Immunogen

Synthetic peptide taken within amino acid region 300-342 on human P2Y12 protein.

Accession #

NCBI:  NP_795345.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.57-0.68 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:100

Dot Blot

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9H224

Overview

Serves as a receptor for ADP and ATP that is coupled to G-proteins that inhibit the adenylyl cyclase second messenger system.  It is necessary for platelet aggregation and blood coagulation.

Molecular Function

G-protein coupled receptor, Transducer, ADP-receptor activity

Subcellular Location

Cell membrane; Multipass membrane protein

Expression

It is highly expressed in the platelets with lower levels of expression found in the brain, and is also expressed in the spinal cord and fetal brain.  The lowest levels of expression are found in the lung, appendix, pituitary and adrenal gland.

Alternative Nomenclature

ADP glucose receptor antibody

ADPG R antibody

ADPGR antibody

BDPLT8 antibody

G protein coupled receptor SP1999 antibody

Gi coupled ADP receptor HORK 3 antibody

HORK 3 antibody

P2RY 12 antibody

P2T(AC) antibody

P2Y 12 antibody

P2Y purinoceptor 12 antibody

P2Y(ADP) antibody

P2Y(cyc) antibody

P2Y12 antibody

P2Y12 platelet ADP receptor antibody

Platelet ADP receptor antibody

Purinergic receptor P2RY12 antibody

Purinergic receptor P2Y G protein coupled 12 antibody

Purinergic receptor P2Y12 antibody

Putative G protein coupled receptor antibody

SP 1999 antibody

General Information

Product

P2Y1 Antibody

Description

Affinity Purified P2Y purinoceptor 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Cat, Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 360-410 on rat P2Y1.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.85 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P49651

Overview

Serves as a receptor for extracellular adenine nucleotides, for example ATP and ADP.  It may mediate some effects of extracellular ATP on insulin secretion in the pancreatic islets.

Molecular Function

G-protein coupled receptor, Transducer, Receptor

Subcellular Location

Cell membrane; Multipass membrane protein

Expression

Is found to be expressed in muscle, heart, liver, kidney, lung, brain, spleen.  Not expressed in testis.

Alternative Nomenclature

ATP receptor antibody

P2 purinoceptor subtype Y1 antibody

P2RY1 antibody

P2RY1_HUMAN antibody

P2Y purinoceptor 1 antibody

P2Y1 antibody

P2Y1 purinoceptor antibody

Platelet ADP receptor antibody

Purinergic receptor antibody

Purinergic receptor P2Y G protein coupled 1 antibody

Purinergic receptor P2Y1 antibody