General Information |
|
Product |
ASIC2 Antibody FITC |
Description |
FITC-Conjugated Acid-sensing ion channel 2 Antibody |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 450-512 on human Acid-sensing ion channel 2 protein. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5-1.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
FITC-Conjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:50,000 |
Immunoprecipitation |
1:200 |
Western Blot |
1:2,500-1:5,000 |
|
|
Uniprot # |
|
Overview |
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li+ and K+. Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate. |
Molecular Function |
acid-sensing ion channel activity; ion gated channel activity; ligand-gated sodium channel activity |
Subcellular Location |
Cell membrane; Multi-pass membrane protein |
Expression |
Brain and spinal cord. Isoform 1 is also detected in testis, liver, colon and ovary. |
Structure |
Homotrimer or heterotrimer with other ASIC proteins. |
Alternative Nomenclature |
ACCN1 antibody Acid sensing ion channel 2 antibody Amiloride sensitive brain sodium channel antibody Amiloride sensitive cation channel 1 neuronal antibody ASIC2 antibody BNaC1 antibody Brain sodium channel 1 antibody Degenerin antibody Mammalian degenerin homolog antibody MDEG antibody Neuronal amiloride sensitive cation channel 1 antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
---|---|---|---|---|
|
ASIC2-201AP | |||
|
ASIC2-BIOTIN | |||
|
P-ASIC2 | |||
|
PC-ASIC2 | |||
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