General Information

Product

hCG beta 2 Antibody

Description

Affinity Purified Choriogonadotropin subunit beta 2 Antibody N-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 50-100 on human choriogonadotropin subunit beta variant 2 protein.

Specificity

This antibody will detect CGB2 only.

Accession #

GenBank: AAH69367.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.63 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

H9KV56

Overview

Stimulates ovaries to synthesize the steriods that are essential for the maintenance of pregnancy

Molecular Function

Hormone

Subcellular Location

Secreted

Expression

Placenta

Structure

Belongs to glycoprotein hormones subunit beta family

Alternative Nomenclature

CG beta antibody

CGB antibody

CGB2 antibody

Chorionic gonadotropin beta 2 subunit antibody

Chorionic gonadotropin beta chain antibody

Chorionic gonadotropin beta polypeptide antibody

hCGB2 antibody

Human Chorionic Gonadotropin antibody

General Information

Product

hCG beta 2 Antibody

Description

Affinity Purified Choriogonadotropin subunit beta 2 Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 82-132 on human choriogonadotropin subunit beta variant 2 protein.

Specificity

This antibody will detect CGB2 only.

Accession #

GenBank: AAH69367.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.63 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

H9KV56

Overview

Stimulates ovaries to synthesize the steriods that are essential for the maintenance of pregnancy

Molecular Function

Hormone

Subcellular Location

Secreted

Expression

Placenta

Structure

Belongs to glycoprotein hormones subunit beta family

Alternative Nomenclature

CG beta antibody

CGB antibody

CGB2 antibody

Chorionic gonadotropin beta 2 subunit antibody

Chorionic gonadotropin beta chain antibody

Chorionic gonadotropin beta polypeptide antibody

hCGB2 antibody

Human Chorionic Gonadotropin antibody

General Information

Product

ABHD2 Antibody

Description

Affinity Purified a/b hydrolase II Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 200-250 on  mouse a/b hydrolase II protein.

Accession #

GenBank: AAQ12022.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q9QXM0

Overview

Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Involved in acrosomal reaction (PubMed:26989199). May also play a role in smooth muscle cells migration.

Molecular Function

Hydrolase, Serine esterase

Subcellular Location

Cell membrane; Single-pass type II membrane protein

Cytoplasmic vesicle › secretory vesicle › acrosome membrane

Expression

Widely expressed with higher expression in testis. Expressed by vascular smooth muscle cells, non vascular smooth muscle cells and heart.

Structure

Signal-anchor, Transmembrane, Transmembrane helix

Alternative Nomenclature

abhydrolase domain containing 2 antibody

alpha/beta hydrolase domain containing protein 2 antibody

HS1 2 antibody

LABH2 antibody

Lung alpha/beta hydrolase 2 antibody

PHPS1 2 antibody

protein PHPS1-2 antibody

General Information

Product

Legumain Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 100-150 on human Legumain protein.

Accession #

NCBI:  XP_016876954

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q99538

Overview

Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.

Subcellular Location

Lysosome

Expression

Ubiquitous. Particularly abundant in kidney, heart and placenta.

Structure

In the zymogen form, the uncleaved propeptide blocks access to the active site.

Alternative Nomenclature

AEP antibody
Asparaginyl endopeptidase antibody
cysteine 1 antibody
Cysteine protease 1 antibody
Legumain antibody
LGMN antibody
LGMN1 antibody
Protease antibody
Protease cysteine 1 (legumain) antibody
Protease cysteine 1 antibody
PRSC1 antibody

General Information

Product

Aromatase Antibody

Description

Affinity Purified Aromatase Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 400-450 on human Aromatase protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

P11511

Overview

Catalyzes the formation of aromatic C18 estrogens from C19 androgens.

Molecular Function

aromatase activity

electron carrier activity

heme binding

iron ion binding

Subcellular Location

Membrane; Peripheral membrane protein

Expression

Widely expressed, including in adult and fetal brain, placenta, skin fibroblasts, adipose tissue and gonads.

Structure

Belongs to the cytochrome P450 family.

Alternative Nomenclature

ARO antibody

ARO1 antibody

Aromatase antibody

CP19A_HUMAN antibody

CPV1 antibody

CYAR antibody

Cyp19a1 antibody

CYPXIX antibody

Cytochrome P-450AROM antibody

Cytochrome P450, family 19, subfamily A, polypeptide 1 antibody

Cytochrome P450, subfamily XIX (aromatization of androgens) antibody

Estrogen synthase antibody

Flavoprotein linked monooxygenase antibody

Microsomal monooxygena

450AROM antibody

General Information

Product

Phospho-Cofilin Antibody

Description

Affinity Purified Phosphorylated Cofilin Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to amino acids within region 1-50 on human Phosphorylated Cofilin.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Modification

Phosphorylated

Storage

-20?C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500-1:5,000

Protein

Uniprot #

P23528

Overview

Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity (PubMed:11812157). In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (PubMed:15580268). Required for the centralization of the mitotic spindle and symmetric division of zygotes (By similarity).

Molecular Function

actin filament binding

Subcellular Location

Plasma membrane, Cytoskeleton, Nucleus

Expression

Widely distributed in various tissues.

Structure

Belongs to the actin-binding proteins ADF family.

Alternative Nomenclature

18 kDa phosphoprotein antibody

CFL 1 antibody

CFL antibody

CFL1 antibody

COF1_HUMAN antibody

Cofilin 1 antibody

Cofilin 1 non muscle antibody

Cofilin antibody

Cofilin non muscle isoform antibody

Cofilin-1 antibody

epididymis secretory protein Li 15 antibody

HEL-S-15 antibody

non-muscle isoform antibody

p18 antibody

General Information

Product

TNF alpha Antibody

Description

Affinity Purified Tumor necrosis factor alpha Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide corresponding to amino acids within region 100-150 on human Tumor necrosis factor alpha protein.

Physical Properties

Quantity

100 µg

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Conjugate

Unconjugated

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20°C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:50-1:100

Immunofluorescence

1:50-1:100

Immunohistochemistry

1:50-1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P01375

Molecular Function

cytokine activity

identical protein binding

protease binding

transcription cis-regulatory region binding

tumor necrosis factor receptor binding

Subcellular Location

Extra cellular secreted, plasma membrane

Structure

Signal-anchor, Transmembrane, Transmembrane helix

Alternative Nomenclature

APC1 antibody

Cachectin antibody

DIF antibody

Differentiation inducing factor antibody

Macrophage cytotoxic factor antibody

Tnf antibody

TNF superfamily member 2 antibody

TNF, macrophage derived antibody

TNF, monocyte derived antibody

TNF-a antibody

TNF-alpha antibody

TNFA antibody

TNFA_HUMAN antibody

TNFSF2 antibody

Tumor necrosis factor (TNF superfamily member 2) antibody

Tumor necrosis factor alpha antibody

Tumor necrosis factor antibody

Tumor necrosis factor ligand superfamily member 2 antibody

Tumor Necrosis Factor, Membrane Form antibody

Tumor necrosis factor, soluble form antibo