General Information |
|
Product |
5HT2C Receptor Antibody BIOTIN |
Description |
BIOTIN-Conjugated 5-hydroxytryptamine receptor 2C Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 400-458 on human 5-hydroxytryptamine receptor 2C. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
BIOTIN-Conjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:50,000 |
Immunocytochemistry |
1:50-1:100 |
Immunohistochemistry |
1:50-1:100 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. |
Molecular Function |
G-protein coupled receptor, Receptor, Transducer |
Subcellular Location |
Cell membrane, Multi-pass membrane protein |
Expression |
Detected in brain. |
Structure |
The PDZ domain-binding motif is involved in the interaction with PATJ, CASK, APBA1, DLG1 and DLG4. |
Alternative Nomenclature |
5 Hydroxytryptamine 2C receptor antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
5HT2C-301AP | |||
|
5HT2C-FITC | |||
|
P-5HT2C | |||
|
PC-5HT2C | |||
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