General Information |
|
Product |
CCR4 Antibody FITC-Conjugated |
Description |
FITC-Conjugated C-C chemokine receptor type 4 Antibody |
Verified Applications |
CF, DB, ELISA, IF, IHC, IMM, WB |
Host |
Rabbit |
Species Cross Reactivity |
Cat, Human, Monkey, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 1-50 on human C-C chemokine receptor type 4 protein. |
Accession # |
NCBI: NP_005499 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.68 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
Confocal Microscopy |
1:250 |
Immunocytochemistry |
1:250 |
Immunofluorescence |
1:250 |
Immunohistochemistry |
1:250 |
Immunoprecipitation |
1:250 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Receptor for C-C type chemokines CCL17/TARC and CCL22/MDC. Functions as chemoattractant homing receptor on circulating memory lymphocytes and as coreceptor for some primary HIV-2 isolates. Can also mediate hippocampal-neuron survival. |
Molecular Function |
GPCR, Receptor, Transducer. |
Subcellular Location |
Cell membrane; Multi-pass membrane protein |
Expression |
Thymus, peripheral blood leukocytes including T-cells, CD4+ cells, basophils and in platelets. Expressed less in spleen and in monocytes. Also found in macrophages, IL-2-activated natural killer cells and skin-homing memory T-cells, mostly the ones expresseding cutaneous lymphocyte antigen. Expressed in brain and microvascular and coronary artery endothelial cells. |
Structure |
Belongs to G-protein coupled receptor 1 family. Interacts with CREB3. |
Alternative Nomenclature |
CD194 antibody ChemR13 antibody CKR4 antibody CMKBR 4 antibody HGCN 14099 antibody K5 5 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
CCR4-401AP | |||
|
P-CCR4 | |||
|
CCR4-BIOTIN | |||
|
PC-CCR4 | |||
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