General Information |
|
Product |
BMPR1A Antibody FITC |
Description |
FITC-Conjugated Bone morphogenetic protein receptor type-1A Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 460-510 on human Bone morphogenetic protein receptor type-1A. |
Accession # |
NCBI: NP_004320 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
FITC-Conjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:10,000 |
Immunohistochemistry | 1:50-1:150 |
Immunoprecipitation |
1:150 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6. |
Molecular Function |
Kinase, Receptor, Serine/threonine-protein kinase, Transferase |
Subcellular Location |
Membrane; Single-pass type I membrane protein |
Expression |
Highly expressed in skeletal muscle. |
Structure |
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. Contains 1 GS domain. Contains 1 protein kinase domain. |
Alternative Nomenclature |
Activin A receptor type II like kinase 3 antibody Activin receptor like kinase 3 antibody ACVRLK 3 antibody ALK 3 antibody BMP type-1A receptor antibody BMPR 1A antibody Bmpr antibody Bone morphogenetic protein receptor type-1A antibody BR1a antibody CD292 antibody Serine threonine protein kinase receptor R5 antibody SKR5 antibody zBMPR IA antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
BMPRA1-101AP | |||
|
BMPRA1-BIOTIN | |||
|
P-BMPRA1 | |||
|
PC-BMPRA1 | |||
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