General Information
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Product
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ROR1 Antibody FITC-Conjugated
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Description
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FITC-Conjugated Receptor tyrosine kinase-like orphan receptor 1 Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey, Mouse, Rat
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Immunogen
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Synthetic peptide corresponding to C terminal amino acids 900-918 on Human ROR1 protein. Peptide was coupled to a carrier protein using heterobifunctional cross linker.
Sequence:
TVKGNKSQKPYKIDSKQAS
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Specificity |
This antibody does not cross react to any other cellular protein. |
Accession #
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GenBank: EAX06557.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunohistochemistry |
1:50-1:150 |
Immunoprecipitation |
1:200 |
Western Blot
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1:500
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Protein
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Uniprot #
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UPI0000EE3178
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Overview
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Tyrosine-protein kinase receptor whose role is not yet clear.
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Molecular Function
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ATP binding; transmembrane receptor protein Tyrosine kinase activity; Wnt-protein binding
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Subcellular Location
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Membrane; Single-pass type I membrane protein
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Expression
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Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm.
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Structure
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Contains 1 FZ (frizzled) domain; Contains 1 Ig-like C2-type (immunoglobulin-like) domain; Contains 1 Kringle domain; Contains 1 Protein kinase domain
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Alternative Nomenclature
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dJ537F10.1 antibody
MGC99659 antibody
Neurotrophic tyrosine kinase antibody
Receptor tyrosine kinase like orphan receptor 1 antibody
receptor-related 1 antibody
RGD1559469 antibody
RP11 24J23.1 antibody
Tyrosine kinase like orphan receptor 1 antibody
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