General Information |
|
Product |
ATG16L1 Antibody BIOTIN |
Description |
BIOTIN-Conjugated Autophagy-related protein 16-1 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Mouse, Rat Predicted: Human
|
Immunogen |
Synthetic peptide taken within amino acid region 560-610 on human Autophagy-related protein 16-1. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
BIOTIN-Conjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:10,000 |
Immunohistochemistry | 1:50-1:150 |
Immunoprecipitation |
1:150 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane. |
Molecular Function |
Identical protein binding, Ubiquitin-like protein transferase activity |
Subcellular Location |
Cytoplasm, Preautophagosomal structure membrane, Peripheral membrane protein |
Structure |
Homooligomer. Interacts with WIPI2, FIP200 and ATG5. Part of either the minor and major complexes respectively composed of 4 sets of ATG12-ATG5 and ATG16L1 (400 kDa) or 8 sets of ATG12-ATG5 and ATG16L1 (800 kDa). Interacts with RAB33B. Interacts with TMEM |
Alternative Nomenclature |
APG16 like 1 antibody APG16L antibody APG16L beta antibody ATG16 autophagy related 16 like 1 antibody ATG16A antibody ATG16L antibody Autophagy related protein 16 1 antibody IBD10 antibody WD repeat domain 30 antibody WDR30 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
ATG16L1-101AP | |||
|
ATG16L1-FITC | |||
|
P-ATG16L1 | |||
|
PC-ATG16L1 | |||
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